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Found 61 neurology trials

A listing of neurology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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The International MS Microbiome Study
18 years - 90 years
All genders
Dr. Amit Bar-Or, MD, FRCPC from the University of Pennsylvania Department of Neurology is conducting a study to investigate how the structure and activity of gastrointestinal microbes (bacteria and fungi) found in the gut contribute to multiple sclerosis pathogenesis. You are being asked to participate in this study because either …
Clinical Core Alzheimer's Disease Core Center (ABC)
75 years - 100 years
All genders
The study is at the Penn Memory Center at the University of Pennsylvania and is under the direction of David Wolk, M.D..  We are currently recruiting normal control participants ages 75 years and older. The purpose of this study is to collect, store and analyze cognitive data  and biological samples, …
Hair Probe to Enhance Cerebral Optical Monitoring of Stroke
99 years or below
All genders
A novel device, developed at the University of Pennsylvania, utilizes diffuse correlation spectroscopy (DCS), which allows for real-time, continuous bedside monitoring of CBF using near infrared light. This non-invasive device holds great promise for monitoring cerebral hemodynamics in stroke patients. Prior work from our group has used this device to …
CHARM- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema following Large Hemispheric Infarction
18 years - 99 years
All genders
Phase 3
Interventional
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number of people with large hemispheric infarction (LHI). These studies suggested that the study drug was safe, did not cause serious side effects or discomfort, and …
Observation of blood pressure and blood flow in your brain (Hemodynamics)for Patients with Left Ventricular Assist Device
18 years - 99 years
All genders
Observational
The research is being conducted to study the relationship between blood pressure and blood flow in your brain. By making these measurements before and after implantation of your left ventricular assist device (LVAD), this study will help understand how the LVAD affects blood flow to your brain.
tDCS to Improve Cognition After Stroke (TRAINS)
18 years - 90 years
All genders
The research study is being conducted in order to determine whether Transcranial Direct Current Stimulation (tDCS) paired with cognitive training can improve thinking abilities in persons with stroke. There will be a total of five stimulation sessions. During the tDCS stimulation, you will be asked to participate in cognitive training.
TEGSEDI Administration in Patients with Polyneuropathy of Hereditary Transthyretin-mediated Amyloidosis (hATTR-PN)
18 years - 99 years
All genders
Phase 4
TEGSEDI (also known as inotersen) is a medicine that has been approved in the United States, Europe and Canada to treat polyneuropathy (nerve damage) caused by hereditary transthyretin amyloidosis (hATTR-PN) in adults. hATTR-PN is a rare genetic disease that worsens over time if left untreated. This research study will examine …
99 years or below
All genders
The purpose of this study is to validate a video-administered cognitive assessment for use by the Alzheimer's Disease Research Centers and other research programs whose activities have been interrupted by the COVID19 pandemic, as well as for use in future initiatives when remote testing will enhance achievement of scientific goals. …
99 years or below
All genders
A GLOBAL PROSPECTIVE OBSERVATIONAL REGISTRY OF PATIENTS WITH POMPE DISEASE
99 years or below
All genders
The overall study objectives include evaluating the long-term safety and tolerability of Staccato alprazolam in patients with stereotypical prolonged epilepsy. The study will evaluate the probability of success of repeated treatment with Staccato alprazolam and of repeated treatment with Staccato alprazolam with no recurrence of seizure(s) up to 2 hours …