Found 61 neurology trials
A listing of neurology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Double-blind, double-dummy study in adults with CIDP. Patients will be randomized to receive either investigational ARGX-117 and IVIG-placebo OR active standard-of-care IVIG and ARGX-117-placebo. Blood/urine collection, patient-reported outcomes, physician efficacy assessments, ECGs, AEs/ConMeds, and suicidality assessments will be performed.
To evaluate the clinical efficacy of VIM0423 compared to placebo in individuals with isolated dystonia.
This is a study evaluating Vtx-002 as a potential treatment for ALS. TDP-43 is a protein that is often dysregulated in ALS patients. Vtx-002 is designed to reduce pathological groups of TDP-43, reducing and preventing ALS pathology. Patients will receive a 1 time dose of Vtx-002 and then undergo a …
This is a phase III, double-blind, placebo-controlled study to evaluate the efficacy and safety or NI0752 in participants with Progressive Supranuclear Palsy (PSP). Participants will receive either 50mg of NI0752 or placebo every 12 weeks for 72 weeks via intrathecal injection during the double-blind period followed by an OLE period.
This is a study evaluating SAR446268 as a treatment for DM1. SAR446268 is designed to deliver miRNA to pathological DMPK gene expression that leads to DM1. Patients will receive a 1-time dose of the study drug and then undergo a 5 year follow-up period to monitor safety and efficacy.
To assess the effect of donanemab versus placebo on cognitive and functional progression in participants with established alpha-synuclein and amyloid co-pathology
Clarity is a Phase 3 double-blind, placebo controlled, randomized clinical trial in patients with non-cardioembolic ischemic stroke or high-risk TIA, to determine if the addition of cilostazol to standard-of-care aspirin or clopidogrel reduces major adverse cardiovascular events during long term follow-up
This study investigates the presence of certain brain proteins in people with conditions like Progressive Supranuclear Palsy, Corticobasal Syndrome, genetic Frontotemporal Lobar Degeneration, Parkinson's Disease, Alzheimer's Disease, and healthy individuals. These conditions are collectively known as tauopathies.The study evaluates how a special substance, which can be seen in brain scans, …
The goal of this study is to better understand that which contributes to the long-term recovery of people who have sustained a traumatic brain injury. To better understand an individual’s recovery following a head-injury, we will measure and examine the chemicals released in the brain and blood following the injury. …
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