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Found 61 neurology trials
A listing of neurology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Primary Objective: To determine changes in neurodegeneration over the first year of treatment with anti-amyloid monoclonal antibodies Secondary Objectives: To identify measures that detect and monitor neuroinflammation during anti-amyloid treatment. To explore the interaction between neuroinflammation and neurodegeneration Primary Endpoint: Neuroimaging and blood-based measures of neurodegeneration, cognitive performance Secondary Endpoints: …
Open label extension of RISE, a study of BHV7000 in patients 18+ with focal epilepsy.
Create a foundational resource for conducting and sharing ATN imaging and blood biomarker results in the context of the large clinically heterogenous brain-donor-enrolled multi-ADRC cohort. These imaging-plasma sets will be intrinsically linked to cognitive and neurobehavioral data collection, genetics and eventually neuropathology.
This study will evaluate the safety and efficacy of DM199 in acute ischemic stroke patients who are not eligible for either tPA or mechanical thrombectomy.
STEP is a Randomized, Multifactorial, Adaptive Platform trial that seeks to optimize the care of patients with acute ischemic stroke (AIS) due to large or medium vessel occlusions (LVOs and MVOs).
The objective of this study is to show that inhaled nitric oxide can increase blood flow in the brain after traumatic brain injury, attenuating brain injury and resulting in improved long-term function. We will use optical brain monitoring to determine changes in cerebral perfusion and metabolism by iNO treatment in …
This study aims to assess the safety and tolerability of long-term therapy with XEN1101 in subjects with FOS or PGTCS who have completed Study XPF-010-301, XPF-010-302, or XPF-010-303. Participants MUST HAVE completed one of the prior studies in order to participate.
An Open-Label Extension Study to Assess the Long-term Effect of EDG-5506 on Safety, Biomarkers, and Functional Measures in Adults and Adolescents with Becker Muscular Dystrophy
BHV-8000 is a novel, brain-penetrant, selective dual inhibitor of Tyrosine Kinase 2 (TYK2) and Janus Kinase 1 (JAK1) that is being investigated as a treatment for early Parkinson's disease (PD).
All objectives are listed in section 3 of the protocol, but the primary objective is to evaluate the long-term safety of RAP-219 in participants with focal onset seizures. The primary endpoint is the incidence of treatment-emergent adverse events (TEAEs). The secondary objectives and their associated endpoints can be found in …
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