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Found 389 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Determine if RAS Inhibitors inhibit the in vitro growth of RAS mutant primary human AML cells. This is a pre-clinical evaluation. There is only one outcome to be measured. The assay is a colony forming assay. AML cells form colonies which are manually counted. Endpoint will be a statistically significant …
Determine the safety of short-course palliative RT for pediatric patients with incurable CNS disease, defined as the ability to successfully complete short-course RT without grade 3 or higher toxicity (per CTCAE v5) within 3 months of the final fraction of RT. Determine the effects of short course RT on patient …
The objective of this study is to establish a registry of patients with thalassemia to allow for both cross-sectional and longitudinal assessment of laboratory values and outcomes and to compare how different treatments impact these variables. Patients with a diagnosis of a clinically significant alpha or beta thalassemia syndrome who …
This study aims to determine the long-term effects of CTL019 on patients who were enrolled in UPCC 13413: "Phase IIa Study of Redirected Autologous T-Cells Engineered to Contain Anti-CD 19 Attached to TCR and 4- BB Signaling Domains in Patients with Chemotherapy Relapsed of Refractory CD 19+ Lymphomas". It also …
This study investigates osteoarthritis. It focuses on understanding changes in pain and function when treated with low dose radiotherapy (LDRT).The study evaluates how well certain tools measure changes in pain, function, and well-being in people with osteoarthritis who have not responded to other treatments.Who can participate: Adults aged 18 and …
The purpose of this study is to investigate relapsed or refractory multiple myeloma. It evaluates the effects of combining inobrodib with pomalidomide and dexamethasone.This study evaluates the safety and effectiveness of the investigational medication inobrodib when used with other medicines. It looks at how the combination affects patients with the …
This study aims to learn more about the use of Mirvetuximab soravtansine and Olaparib as a maintenance therapy after completion of prior therapy for recurrent platinum sensitive ovarian, peritoneal and fallopian tube cancer. Mirvetuximab soravtansine is an effective antibody drug conjugate that targets folate receptor alpha. Olaparib is one of …
This study investigates the effects of an investigational medication compared to observation in patients with intermediate risk non-muscle invasive bladder cancer (NMIBC). The study aims to understand how the investigational treatment affects the condition in comparison to standard observation.Participants in the study will either receive the investigational medication or be …
Determine interrater reliability between 3D whole body image assessment and in-person clinical assessment regarding the need for in-person evaluation of keratinocyte carcinomas in high-risk patients. VectraWB360 3D whole-body photography-based assessment by a dermatologist (Approach 1). In-person clinical assessment by a dermatologist (Approach 2). Determine interrater reliability between 3D whole body …
This study investigates the effectiveness of investigational medications for patients with advanced breast cancer who have specific genetic mutations. The purpose of this study is to compare the effects of saruparib plus camizestrant with other treatments chosen by the physician, including CDK4/6 inhibitors and endocrine therapy. The study focuses on …
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