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Found 389 oncology trials

A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 2
Interventional
This study investigates the use of an investigational imaging agent for lung cancer surgery. The purpose of this study is to explore the effectiveness and safety of a single dose of a fluorescence imaging agent administered through intravenous infusion. This agent is used during surgical procedures for patients with Stage …
18 years or above
All genders
Phase 3
Interventional
This study investigates the use of investigational medications for treating advanced or metastatic non-small cell lung cancer (NSCLC) with a specific genetic mutation known as KRAS G12C. The purpose of this study is to compare the effects of calderasib, a targeted therapy, combined with subcutaneous pembrolizumab, against a combination of …
18 years or above
All genders
Phase 2/3
Interventional
This study investigates treatment options for patients with non-small cell lung cancer (NSCLC) that have mutations in the epidermal growth factor receptor (EGFR) gene. Patients in this study have experienced disease progression despite previous treatment with EGFR tyrosine kinase inhibitors, which are medications that block signals promoting cancer cell growth.Participants …
18 years or above
All genders
This study investigates providing access to axicabtagene ciloleucel, an investigational medication, for patients who have a disease approved for treatment with this medication but whose product does not meet commercial release criteria. The purpose is to allow patients to receive treatment with axicabtagene ciloleucel that is otherwise unavailable due to …
99 years or below
All genders
The aim of this cohort study to determine the oncologic and functional outcomes following all patients who underwent the transoral robotic surgery (TORS) in order to compare TORS to other surgical approaches.
UPCC 02520 A Phase 1/2, Umbrella Study with Rolling Arms of Investigational Agents, Pembrolizumab, and Chemotherapy, Alone or in Combination, in Participants with Non-small Cell Lung Cancer (NSCLC).
18 years or above
All genders
Observational
This study investigates treatments for non-small cell lung cancer (NSCLC). The purpose of this study is to evaluate the effectiveness of investigational agents, alone or in combination with pembrolizumab and chemotherapy, in treating NSCLC. Pembrolizumab is a type of immunotherapy that helps the immune system fight cancer cells. The study …
18 years or above
All genders
Phase 3
Interventional
This study investigates treatment options for non-small cell lung cancer (NSCLC), focusing on patients who undergo surgery. The purpose is to determine if adding an investigational medication to pembrolizumab post-surgery is more effective in preventing disease recurrence in patients who did not achieve a pathological complete response (pCR) after initial …
99 years or below
All genders
This study investigates muscle invasive bladder cancer. It examines the effects of combining treatments after initial therapy.This study evaluates how well the combination of treatments works in preventing the need for bladder removal.Who can participate: Eligibility criteria are to be determined.Study details: Participants will receive a combination of investigational medication …
18 years or above
Accepts healthy volunteer
All genders
This study investigates the use of investigational medications, specifically pembrolizumab alone or in combination with lenvatinib, for treating high risk renal cell carcinoma. The purpose of this study is to see how these medications affect the immune system's response to the cancer when given before and after surgery to remove …
18 years - 70 years
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication in combination with chemotherapy for adults with newly diagnosed FLT3-ITD negative acute myeloid leukemia (AML). This trial will compare the investigational medication to a placebo to see if it improves overall survival in these patients.Participants will receive either the investigational medication …
301 - 310 of 389