A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
There is evidence that GALAD, a score that incorporates 3 blood based biomarkers and patient age and sex may be more effective than standard of care screening at detecting HCC early in patients with liver cirrhosis or chronic hepatitis B. Patients undergoing liver cancer screening will be enrolled, then randomized …
The primary outcomes will be to establish the safety and feasibility of inhaled imaging in patients with NSCLCand to develop a robust RT planning protocol incorporating both standard of care metrics and those derived from inhaled imaging
This study will evaluate the efficacy and safety of giredestrant plus everolimus compared with exemestane plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer who have had previous treatment with CDK4/6is and endocrine therapy, either in the locally …
This is a Phase III, 2-arm, randomised, open-label study assessing the efficacy and safety of neoadjuvant Dato-DXd plus durvalumab followed by adjuvant durvalumab with or without chemotherapy compared with neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab with or without chemotherapy in participants with previously untreated TNBC or hormone receptor-low/HER2-negative …
We would like to rely on the NCI CIRB as the IRB of record for this study. The purpose of this research study is to compare any good or bad effects of using the chemotherapy drug cabazitaxel (also known as Jevtana®) with the usual approach of the hormone based therapy …
This is a prospective cohort study to document long-term dental and other oral outcomes in patients who receive external beam and modern radiation therapy (RT) modalities with curative intent, as part of clinical care for a head and neck cancer. ORARAD II study will examine participants of the original cohort …
The purpose of the study is to compare risk reducing salpingectomy with delayed oophorectomy to risk-reducing salpingo-oophorectomy in high risk-women.
The main purpose of this research study is to determine the likelihood of cancer growing back in the throat or in the neck, 2 years after completion of radiation, if lower doses of radiation are used to a smaller area of the head and neck region, than is currently the …
The long-term goal of our research program is to identify and target the mechanisms by which innovations in care delivery may facilitate compliance with guideline-concordant care and access to care for early and late stage bladder cancer patients. The objective in this proposal is to evaluate a novel delivery model …
PURPOSE To perform a pivotal study of the next-generation tomosynthesis system with volunteers recruited among women with suspicious breast finding(s), with the goal of assessing the effect of scanning method on characterization of findings as benign or malignant. The primary outcome variable for this 3D mammography imaging study is the …