Found 389 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates breast cancer. It looks at the effects of an investigational medication given before surgery.The purpose of this study is to evaluate the safety and immune effects of the investigational medication. The study will check how the body responds to the treatment.Who can participate: Adults aged 18 and …
The purpose of this study is to investigate locally advanced or metastatic estrogen receptor-positive, HER2-negative breast cancer. This study investigates how the investigational medication performs alone and when combined with another treatment.This study evaluates the safety and how well the investigational medication works. It looks at how the investigational medication …
This study investigates the safety and feasibility of using investigational medications as rescue therapies for conditions related to CAR T cell therapy, specifically cytokine release syndrome (CRS) and hemophagocytic lymphohistiocytosis-like syndrome (CRHLS). These conditions can occur after receiving CAR T cell therapy, which is a treatment that modifies a patient's …
A Phase 2 study to evaluate the clinical activity, safety, and potentially predictive biomarker profile of ZN-c3 in subjects with High-Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
This study investigates the effects of a combination of investigational medications in patients newly diagnosed with secondary acute myeloid leukemia (AML) after previous exposure to hypomethylating agents. The purpose of this study is to understand how these investigational medications work together to treat AML.Participants in the study will receive a …
This study investigates head and neck squamous cell carcinoma (HNSCC). The purpose of this study is to understand the molecular characteristics of HNSCC by profiling biomarkers in tissue and blood samples from patients undergoing their usual care treatment.Participants in this study will have their tissue and blood samples collected for …
The goal of RECIPE (Recruitment and Engagement in Care to Impact Practice Enhancement) for Sickle Cell Disease is to find unaffiliated patients with SCD using three distinct pathways, engage them in care using linkage coordinators and understand the contextual factors and implementation support needed to ensure these methodologies can be …
The purpose of this study is to investigate hematopoietic cell transplantation, other cellular therapies, and marrow toxic injuries. This procedure involves receiving blood-forming stem cells to restore bone marrow function, often used for treating certain cancers and blood disorders.Participants in this study will undergo various procedures related to the collection …
This study investigates the long-term safety and efficacy of patients who have undergone CAR-T cell therapy. The purpose of this study is to monitor these patients for 15 years following their last CAR-T infusion to assess any delayed adverse events, check for replication competent lentivirus, and evaluate long-term efficacy, including …
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