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Found 143 Metastatic Cancer trials
A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety and effectiveness of combining two investigational medications, SNDX-5613 and gilteritinib, for treating relapsed or refractory acute myeloid leukemia (AML) with specific genetic mutations. This study focuses on patients whose leukemia has returned or not responded to treatment and who have mutations in the FLT3 gene, …
This study investigates the use of an investigational imaging agent for lung cancer surgery. The purpose of this study is to explore the effectiveness and safety of a single dose of a fluorescence imaging agent administered through intravenous infusion. This agent is used during surgical procedures for patients with Stage …
This study investigates the effectiveness of combining an investigational medication with chemotherapy to treat patients with certain types of sarcomas that have spread or cannot be surgically removed. The purpose of this study is to determine if adding the investigational medication to standard chemotherapy can improve outcomes for patients with …
This study investigates the use of an investigational medication in treating patients with Kaposi sarcoma. The purpose of this study is to evaluate how well the investigational medication works by blocking certain enzymes needed for tumor cell growth, which may stop the tumor from growing.Participants will receive the investigational medication …
This study investigates the use of unlicensed cryopreserved cord blood units (CBUs) for transplantation in pediatric and adult patients with hematologic malignancies and other conditions. The purpose of this study is to understand how well patients recover neutrophil levels, a type of white blood cell important for fighting infections, after …
This study investigates the effects of adding an investigational medication, a type of immunotherapy, to chemotherapy before surgery in patients with high-grade upper tract urothelial cancer. Immunotherapy uses substances to stimulate or support the immune system to fight cancer, while chemotherapy uses drugs to kill or slow the growth of …
This study investigates harm-reduction sampling in individuals who are unmotivated to quit smoking. The purpose is to compare how different products, such as e-cigarettes and oral nicotine pouches, affect smoking behavior in comparison to a medicinal nicotine control condition like nicotine patches and lozenges. Participants will be randomly assigned to …
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The purpose of this study is to investigate different biopsy strategies during colonoscopy for patients with Inflammatory Bowel Disease (IBD). This study focuses on two methods: the limited biopsy strategy, which involves taking fewer random biopsies, and the random biopsy strategy, which involves taking more frequent biopsies throughout the colon. …
This study investigates the effects of total ablative therapy compared to usual systemic therapy in patients with limited metastatic colorectal cancer. Colorectal cancer can spread to other parts of the body, and this study focuses on cases where it has spread to up to four sites. Ablative therapy aims to …
This study investigates an investigational therapy for treating HIV-associated aggressive B-cell non-Hodgkin lymphoma that has either returned or not responded to previous treatments. The purpose is to evaluate the safety and feasibility of using genetically modified T cells, known as CAR-T therapy, which are designed to target a specific protein …
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