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Found 143 Metastatic Cancer trials

A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 2/3
Interventional
This study investigates the effect of adding radiation therapy to the usual maintenance therapy with an investigational medication in patients with extensive stage small cell lung cancer. This study aims to compare the progression-free survival and overall survival of patients receiving the investigational medication alone versus those receiving it with …
18 years or above
All genders
Phase 2
Interventional
This study investigates the combination of an investigational medication, administered as telomelysin (OBP-301), with pembrolizumab in patients with advanced or metastatic gastric or gastroesophageal junction cancer. The purpose of this study is to determine if this combination is safe and effective for patients whose cancer has progressed despite previous treatments.Participants …
18 years - 120 years
Female
Phase 3
Interventional
This study investigates the effectiveness of letrozole, an investigational medication, in comparison to a placebo for postmenopausal women with hormone receptor-positive breast cancer. The purpose of this study is to determine if taking letrozole for five years can improve disease-free survival after completing five years of hormonal therapy, which may …
18 years or above
All genders
Interventional
This study investigates pancreatic cancer. It focuses on a structured lipid medical food designed to address fat malabsorption in patients who have difficulty absorbing fats due to their condition.The purpose of this study is to evaluate the safety, tolerance, and potential effects of the structured lipid medical food. It looks …
18 years or above
All genders
Phase 2/3
Interventional
This study investigates neuroendocrine tumors. It focuses on participants who have previously received treatment for tumors that cannot be removed by surgery or have spread to other parts of the body.This study evaluates the effectiveness of an investigational medication compared to everolimus. It examines how well the treatments work and …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of adding an investigational medication to the standard treatment for patients with metastatic pancreatic cancer who have specific genetic mutations known as BRCA1 or BRCA2. The purpose of this study is to see if the combination of an investigational medication with olaparib, a targeted therapy …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effects of two investigational treatments for patients with differentiated thyroid cancer that does not respond to standard treatment and has a specific genetic change called BRAF V600E mutation. The purpose of this study is to compare the effectiveness and safety of cabozantinib, a receptor tyrosine kinase …
18 years or above
All genders
Phase 3
Interventional
The purpose of this study is to investigate the effect of adding an investigational medication to the immunotherapy drug durvalumab in patients with non-small cell lung cancer (NSCLC) who have undergone chemotherapy and surgery. The study aims to see if the combination of treatments can increase the time patients remain …
18 years or above
All genders
Phase 2
Interventional
This study investigates progressive meningiomas. It looks at how certain investigational medications work for people with this condition.The focus is on evaluating the safety and effectiveness of these investigational medications. The study will see how these medications impact the condition in general.Who can participate: Adults with progressive or residual meningiomas …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
121 - 130 of 143