Found 143 Metastatic Cancer trials
A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effectiveness of two surgical procedures in reducing the risk of ovarian cancer in individuals with BRCA1 mutations. The purpose of this study is to compare bilateral salpingectomy, which involves removing the fallopian tubes, with bilateral salpingo-oophorectomy, which involves removing both the fallopian tubes and ovaries. These …
This study investigates the effectiveness of an investigational medication following surgery and chemotherapy in patients with pancreatic cancer who have specific genetic mutations. The study focuses on patients whose cancer has been surgically removed and who have a mutation in the BRCA1, BRCA2, or PALB2 genes. These genes are known …
This study investigates the effectiveness of combining hormone therapy with or without an investigational medication in treating patients with breast cancer. Hormone therapies like tamoxifen citrate and others work by lowering estrogen levels, potentially slowing or stopping cancer growth. The investigational medication being studied may also stop tumor growth by …
This study investigates non-small cell lung cancer. This study looks at how adding an investigational medication to the usual treatment affects patients with this condition.The study evaluates the safety and effectiveness of the investigational medication when used with standard treatments. It observes how well the treatment works and any side …
This study investigates the use of investigational medications following CAR T-cell therapy for individuals with relapsed or refractory large B-cell lymphoma and grade IIIB follicular lymphoma. The purpose of this study is to determine if additional treatment with investigational medications, after initial chemotherapy and CAR T-cell therapy, can better manage …
This study investigates the effects of adding investigational medications to the usual chemotherapy regimen for patients with peripheral T-cell lymphoma. The purpose of this study is to compare the effectiveness of three different treatment arms: one with the investigational medication duvelisib, another with the investigational medication CC-486, and the third …
This study investigates different treatment approaches for patients with high-risk acute myeloid leukemia (AML), a type of cancer that affects the blood and bone marrow. The study compares the standard treatment of cytarabine and daunorubicin, which are chemotherapy drugs that stop cancer cell growth, with several experimental regimens. These include …
This study investigates the effectiveness of adding investigational medication combinations to the usual chemotherapy in patients with HER2 positive endometrial cancer. The investigational medications, which include monoclonal antibodies like trastuzumab and pertuzumab, target HER2 receptors on cancer cells to block signals for growth and potentially mark the cells for destruction …
This study investigates treatments for adults newly diagnosed with BCR-ABL-positive Acute Lymphoblastic Leukemia (ALL). The purpose of this study is to compare the effectiveness of a standard treatment involving chemotherapy, steroids, and a type of medicine called a tyrosine kinase inhibitor (TKI) with a treatment that adds another medicine called …
This study investigates the effects of an investigational medication on patients with advanced solid tumors that have a KRAS G12D mutation. The purpose is to understand the safety and effectiveness of the investigational medication when used alone and in combination with other treatments.Participants in the study will receive the investigational …
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