Found 143 Metastatic Cancer trials
A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The objectives of this proposal are to: 1) describe the incidence of depression and trajectory of depressive symptoms; 2) identify potential determinants of depression; and 3) characterize the consequences of depression in a large, international cohort of patients with PC and in subgroups of this population during early and late …
This study investigates an investigational medication for patients with advanced non-small cell lung cancer (NSCLC) and other solid tumors that have a specific change in the anaplastic lymphoma kinase (ALK) gene. The purpose of this study is to find out how safe and tolerable the investigational medication is, and to …
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life. In this 802-subject multicenter placebo-controlled randomized clinical trial, the hypothesis to be tested is that the incidence of adverse outcomes …
The overall study objectives include evaluating the long-term safety and tolerability of Staccato alprazolam in patients with stereotypical prolonged epilepsy. The study will evaluate the probability of success of repeated treatment with Staccato alprazolam and of repeated treatment with Staccato alprazolam with no recurrence of seizure(s) up to 2 hours …
Primary Objective To assess whether B.brilliant, a Novel Digital Breast Tomosynthesis System leads to better visualization of calcifications compared to standard wide-angle DBT imaging Secondary Objectives To evaluate the accuracy of NDBT B.brilliant for predicting the number of calcifications and extent of the calcification cluster(s) and morphology compared to standard …
This study investigates the use of a medical device containing yttrium-90 for treating liver cancer, specifically Hepatocellular Carcinoma (HCC). The purpose of this study is to evaluate the safety and effectiveness of Eye90 microspheres, which deliver localized radiation therapy directly to liver tumors. This approach is used for patients whose …
Primary Objectives:To perform metabolic phenotyping of treatment naïve and recurrent GBM by multitracer [18F]Fluciclovine and 18F-FDG PET. Secondary Objectives:To compare uptake measures of 18F-Fluciclovine and 18F-FDG and MRI quantification of glutamate and lactate levels to tumor tissue laboratory assays (RNA seq and proteomics) of glutamine/glutamate, glucose, and lactate metabolism. To …
The aims of this study are four-fold: (1) To determine if cholate clearance is related to underlying cardiovascular hemodynamics, specifically low CO, elevated CVP, desaturation as seen in the Fontan. (2) To characterize Fontan patients with elevated systemic HFR/portal HFR ratio. (3) To know whether cholate clearance is a reliable …
The purpose of this study is to provide access to an investigational treatment for adult patients with acute lymphoblastic leukemia (ALL). This study is focused on patients who have already had a procedure called leukapheresis, where blood cells are collected, and have had an investigational treatment made from their cells, …
We propose an iterative approach to develop and pilot test a new mHealth behavioral intervention for AET adherence that is culturally tailored to Black breast cancer survivors. We will first use qualitative methods informed by Black breast cancer survivors to develop a blueprint of the intervention (Aim 1). We will …
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