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Found 205 Type 2 Diabetes Mellitus trials

A listing of Type 2 Diabetes Mellitus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Matching Perfusion and Metabolic Activity in HFpEF
18-99 years
All genders
Phase 2
This study will test whether Potassium Nitrate (KNO3), with and without Propionyl-L-Carnitine (PLC) and Nicotinamide Riboside (NR), improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity (SkM OxPhos) in participants with Heart Failure with Preserved Ejection Fraction (HFpEF). This study will also test whether the response to supplemental oxygen …
 I-SPY COVID TRIAL: An Adaptive Platform Trial to Reduce Mortality and Ventilator Requirements for Critically Ill Patients
18-99 years
All genders
Interventional
A trial to compare different investigational agents for their ability to improve clinical outcomes n severely ill patients with COVID-19 pneumonia.
 PRESTA- Promoting Recovery after Stroke with Amantadine
18-99 years
All genders
Phase 2
The research team aims to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial. We will randomize patients post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine. Patients will be on study drug or placebo for 1 month but will …
 Brain Arterio-Venous Metabolomic Profiling
18-99 years
All genders
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
 Size and Decay of HIV-1 Reservoirs in Tissues and Cerebrospinal Fluid in Participants on Long-Term Antiretroviral Therapy
18-99 years
All genders
The purpose of this study is to look at where human immunodeficiency virus (HIV) might be “hiding” when standard lab tests show that HIV levels in the blood are very low.
 Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1
18-99 years
All genders
Phase 2
Interventional
This study will assess the safety, tolerability, pharmacokinetics, and antiviral activity of long-acting cabotegravir (CAB LA) plus the broadly neutralizing monoclonal antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), in adults living with HIV-1 with suppressed plasma viremia.
 Evaluating Using Rescue Therapies for CAR T cell Related Cytokine Release Syndrome (CRS) and HLH-like Syndrome
18-99 years
All genders
Interventional
This research study is being conducted to evaluate experimental rescue therapies for the treatment of cytokine release syndrome (CRS) and CAR T cell related HLH-like syndrome (CRHLS). These are both life-threatening side effects which can occur in some patients after infusion with a CAR T cell product. This consent allows …
99 years and younger
All genders
Compare the safety and efficacy of the Bare Temporary Spur Stent System in subjects with infrapopliteal critical limb ischemia (CLI) to a pre-defined performance goal based on standard percutaneous transluminal balloon angioplasty (PTA). Population: infrapopliteal CLI, Rutherford class 4-5, not considered amenable to conservative medical therapy and require endovascular intervention …
99 years and younger
All genders
Primary: To determine whether TcMS can reduce the burden of VT in patients with VT storm. Secondary: 1. To determine whether low frequency TcMS or TcMS with TBS is more effective at reducing the burden of VT in patients with VT Storm. 2. To determine the safety of TcMS in …
99 years and younger
All genders
Please see Section 3 of the full protocol. Please see Section 3 of the full protocol. Please see Section 3 of the full protocol.
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