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Found 205 Type 2 Diabetes Mellitus trials

A listing of Type 2 Diabetes Mellitus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Corrona PsA-SpA Registry

99 years and younger
All genders
Request to rely on New England Institutional Review Board Request to rely on New England Institutional Review Board Request to rely on New England Institutional Review Board
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ENGAGE

99 years and younger
All genders
This is a phase 2/3, multicenter, randomized, 3-part study investigating the efficacy, safety, tolerability, PK, and immunogenicity of dupilumab in adults and adolescents (12 years of age) with active EoG (with or without EoD).Eosinophilic gastritis (EoG) is a rare, chronic, allergic/immune mediated disease of the stomach, distinct from eosinophilic esophagitis …
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Sanofi

99 years and younger
All genders
The dupilumab clinical program in EoE has provided evidence that long-term suppression of IL-4 and IL-13 could lead to progressive improvement in fibrostenosis. . There is a need for longer term assessments with comprehensive functional, histological, molecular, clinical, and endoscopic assessments to characterize the risk of fibrotic progression as well …
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BDPI-20-004

99 years and younger
All genders
For a detailed list of objectives, please refer to Section 3, "Objectives" in the latest protocol. For a detailed list of primary outcomes, please refer to the Section 3.1, "Primary Endpoints" in the latest protocol. For detailed list of secondary outcomes, please refer to Section 3.2, " Secondary Endpoints" in …
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Abbvie 430

99 years and younger
All genders
We are requesting a reliance agreement with an external IRB, Advarra. The purpose of this study is to evaluate the safety of upadacitinib and as well PK of upadacitinib as maintenance treatment in subjects with moderate to severe CD who have responded to upadacitinib induction treatment in Study M14-431.
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NN7730

99 years and younger
All genders
Effects of NNC0194-0499 alone and in combination with semaglutide, of semaglutide alone, and of cagrilintide alone and in combination with semaglutide on liver damage and alcohol use in people with alcohol-related liver disease
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NOTCH Study

99 years and younger
All genders
Notch signaling plays a key role in regulating stem cell differentiation in the GI tract, with increased Notch activity promoting absorptive lineage differentiation, and Notch inhibition resulting in secretory lineage differentiation including goblet cells, the hallmark of esophageal intestinal metaplasia. Notch may be particularly relevant to BE and progression to …
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ATLAS-UC

99 years and younger
All genders
To evaluate the efficacy, safety, and tolerability of multiple does strengths of MK-7240 IV infusion and subcutaneous injection compared to Placebo as assessed by the proportion of participants achieving clinical remission per Modified Mayo Score, endoscopic improvements, at designated time points. Participants aged 16 to 75 years (inclusive) with moderately …
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PHIN-001

99 years and younger
All genders
Please see section 2 of the protocol, under "Introduction" for a list of study objectives. Please see section 2 of the protocol, under "Objectives" for a list of primary outcome variables. Please see section 2 of the protocol, under "Objectives" for a list of secondary outcome variables.
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AK-US-001-0105

99 years and younger
All genders
The primary objective of this study is to evaluate the effect of EFX compared to placebo on achieving NASH resolution AND fibrosis regression in subjects with fibrosis stage 2 or 3 at Week 52. Subjects meeting the study's eligibility criteria will randomly assigned in a 1:1:1 ratio to 1 of …
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