Found 205 Type 2 Diabetes Mellitus trials
A listing of Type 2 Diabetes Mellitus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This is a Phase 3, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of EFX in subjects with noninvasively diagnosed NASH/NAFLD. Subjects will be dosed QW with EFX 50 mg or placebo for up to 52 weeks. The safety and tolerability of EFX will be assessed during the study …
The overarching goal of our Clinical Validation Center for Hepatocellular Carcinoma (CVC-HCC) is to develop a robust infrastructure that will support efficient validation of emerging HCC biomarkers. Our CVC-HCC will also conduct studies to validate novel blood and imaging biomarkers to improve risk stratification and early detection in patients with …
A Study to Investigate the Efficacy and Safety of Solrikitug in Adults with Eosinophilic Esophagitis
Solrikitug is a humanized immunoglobulin (Ig) G1 monoclonal antibody that binds to human thymic stromal lymphopoietin TSLP is an up-stream regulator of the T-helper 2 immune response and has been shown to drive the Th2 inflammatory responses that are involved in allergic inflammatory disorders, including eosinophilic esophagitis (EoE). This is …
There is evidence that GALAD, a score that incorporates 3 blood based biomarkers and patient age and sex may be more effective than standard of care screening at detecting HCC early in patients with liver cirrhosis or chronic hepatitis B. Patients undergoing liver cancer screening will be enrolled, then randomized …
A 52-week, Double-blind, Placebo-controlled, Randomized, Phase 3 study Intended to Determine the Effects of seladelpar on normalization of Alkaline phosphatase Levels in Subjects with Primary Biliary Cholangitis (PBC) and an Incomplete Response or Intolerance to Ursodeoxycholic Acid (UDCA)
Determine whether oral BHB supplementation is safe and tolerable in FAP. Determine whether oral BHB supplementations increases serum BHB levels in FAP. Investigate whether oral BHB supplementation leads to transcription and protein expression changes in the intestinal mucosa and polyps in FAP. Elucidate whether oral BHB supplementation in FAP reduces …
To evaluate the efficacy and safety of 2 different doses of daplusiran/tomligisiran (50 mg every 4 weeks and 200 mg every 4 weeks for a total of 6 doses) followed by bepirovirsen 300 mg weekly for 24 weeks (with loading doses) in people living with chronic HBV on nucleos(t)ide analogue …
The purpose of the study is to compare how amlodipine versus metoprolol effect blood pressure in people with HFpEF. While hypertension is the most common risk factor for HFpEF, there is little evidence on the potential role of common antihypertensive medications, specifically calcium channel blockers (like amlodipine) and β-blockers …
The research study is being conducted to test an experimental vaccine to potentially prevent cancer for people with BRCA1 or BRCA2 mutations. This study will test if the vaccine is safe (without significant side effects) and test a new way of administering vaccines. It will also test whether the vaccine …
This will be an observational study to investigate the feasibility and efficacy of a home-based, tech enabled, remotely supervised, cardiac rehabilitation (CR) program in qualifying American adults who cannot participate in traditional center based rehab.This study aims to investigate the feasibility and effectiveness of Carda Healths remotely administered cardiac rehab …
