Found 129 surgery trials
A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effectiveness of different treatment combinations for Stage I HER2-positive breast cancer. The purpose of this study is to compare the side effects and long-term benefits of two different HER2-directed therapies used after surgery. Participants will be randomly assigned to one of two study arms: one receiving …
This study investigates the use of polygenic risk scores (PRS) and novel early detection strategies in women at risk for ovarian cancer. The purpose of this study is to understand how women incorporate these tools in their decisions about cancer screening and risk-reducing surgery. Researchers will conduct qualitative interviews with …
This study will assess the ex vivo use of established and in-house near-infrared fluorophores for imaging brain tumors. Fluorophores will be topically applied to freshly excised tumor specimens for imaging on the surgical back table. Participants are patients undergoing surgery for CNS tumors who consent to use of their specimens. …
This study investigates the effectiveness of an investigational medication following surgery and chemotherapy in patients with pancreatic cancer who have specific genetic mutations. The study focuses on patients whose cancer has been surgically removed and who have a mutation in the BRCA1, BRCA2, or PALB2 genes. These genes are known …
This will be a prospective, observational, multicenter study. All implants will be placed in the maxilla or mandible for already established participants at Penn Dental Medicine. The patient will either have a temporary prosthesis placed (out of occlusion) immediately (during the same implant placement visit or within 48 hours) or …
This study investigates digital mindfulness-based interventions for younger breast cancer survivors who experience elevated depressive symptoms. The purpose of this study is to compare two different digital approaches: one that is live and instructor-led via Zoom, and another that is self-paced and app-based. Participants are breast cancer survivors diagnosed at …
This research study is being conducted to collect information on those who have been diagnosed with a disease related to a heart valve dysfunction or abnormality, needing surgical repair, or replacement of the affected valve. This research study is collecting information about the disease and the treatment. Participants will be …
The TMD-PRIME study will be a repository for DNA, RNA, plasma, serum, bone, & tissue from patients enrolled at the Penn Center for Temporomandibular Joint Disease (TMD). TMD-PRIME will create a bio-specimen & data repository by integrating efforts of researchers focused on the study of causes, detection, treatment, & prevention …
This is an observational study to evaluate the concordance rate between the results of performing intraoral exams by viewing live and/or recorded video footage of subjects' oral cavities and the results of standard in-person intraoral exams. Adult subjects capable of providing Informed Consent will undergo a routine intraoral exam by …
The objective of this study is to obtain neural recordings from deep brain structures while performing simple intraoperative tasks in order to improve the understanding of temporal relationship of deep neural signals and the performance of simple psychomotor, cognitive, and/or executive tasks. The standard DBS surgery provides an opportunity to …
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