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Found 180 medicine trials

A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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UPCC 05519 A Phase II, Single-Arm Study Of Carboplatin, Weekly Taxane, And Ramucirumab In Advanced Non-Small Cell Lung Cancer (NSCLC) After Progressive Disease On Chemoimmunotherapy
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of a combination of three investigational medications in treating advanced non-small cell lung cancer (NSCLC). The purpose of this study is to see if these medications can shrink tumors or slow their growth in participants who have previously received chemotherapy and immunotherapy.Participants in this study …
18 years or above
All genders
Interventional
This study investigates the impact of different outreach strategies on a telehealth-delivered collaborative care program for patients with lung cancer. The purpose is to compare two approaches: a more intensive 'high touch' strategy versus a standard outreach. The study focuses on patients who are experiencing depression and/or anxiety, which are …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effects of investigational medications like hydroxychloroquine and avelumab, with or without palbociclib, on early-stage ER+ breast cancer patients. These patients have disseminated tumor cells (DTCs) in their bone marrow after surgery and standard therapy. The purpose is to understand how these medications can target DTCs, which …
18 years or above
Female
Phase 1
Interventional
This study investigates the safety and tolerability of an investigational medication for women with hormone receptor-positive (HR+) and human epidermal growth factor receptor 2 negative (HER2-) metastatic breast cancer. The study focuses on participants whose tumors have mutations in the PIK3CA gene. The purpose is to find the safest and …
18 years or above
All genders
Interventional
The purpose of this study is to investigate different biopsy strategies during colonoscopy for patients with Inflammatory Bowel Disease (IBD). This study focuses on two methods: the limited biopsy strategy, which involves taking fewer random biopsies, and the random biopsy strategy, which involves taking more frequent biopsies throughout the colon. …
18 years or above
All genders
Interventional
This study investigates two different ways to manage lymphedema in individuals who have survived head and neck cancer. This study compares clinic-based Complete Decongestive Therapy (CDT) with a home-based hybrid model of CDT to see how each approach affects the severity of lymphedema in participants.Participants will either receive CDT in …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of an investigational medication combined with ipilimumab in patients with metastatic pancreatic cancer. The purpose is to understand if this combination can slow tumor growth and what side effects may occur. Participants will be placed into two study arms: Arm A will receive the investigational …
75 years - 85 years
Accepts healthy volunteer
All genders
This study investigates the impact of a decision aid on colorectal cancer screening behaviors among older adults with low health literacy. The purpose of this study is to see if a newly developed decision aid pamphlet can influence the screening intentions of adults aged 75-85, who may have different risk …
21 years or above
Accepts healthy volunteer
All genders
This study investigates harm-reduction sampling in individuals who are unmotivated to quit smoking. The purpose is to compare how different products, such as e-cigarettes and oral nicotine pouches, affect smoking behavior in comparison to a medicinal nicotine control condition like nicotine patches and lozenges. Participants will be randomly assigned to …
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Online study
18 years or above
All genders
Interventional
This study investigates the effects of photobiomodulation therapy (PBMT) on chronic lymphedema in survivors of head and neck cancer. PBMT is a type of light therapy that has been approved by the U.S. Food and Drug Administration for treating arm lymphedema related to breast cancer. This study aims to confirm …
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