Found 180 medicine trials
A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates PARP-1 expression in men with metastatic prostate cancer using a special imaging technique called PET/CT scans. The purpose of this study is to observe how a radiotracer, which is a substance used to highlight areas of the body in imaging tests, interacts with cancerous sites in the …
This study investigates the effectiveness of 'nudges' to clinicians, patients, or both in increasing referrals to and engagement with tobacco use treatment services (TUTS) for people with HIV. The purpose of this study is to compare these strategies to usual care in a four-arm pragmatic cluster randomized clinical trial. The …
This study investigates the effects of an investigational medication on patients with myelofibrosis or myelodysplastic syndrome who also have anemia. Participants in the study will receive the investigational medication, and researchers will monitor its safety, tolerability, and how it affects the body, including its impact on anemia. The study includes …
This study investigates the effectiveness of a quantitative HER2 assay in distinguishing between patients with HER2 IHC1+ metastatic breast cancer who respond to treatment and those who do not. The purpose is to determine if this assay can reliably identify patients who are likely to benefit from receiving investigational medications …
This study investigates an imaging technique using an investigational medication and a special camera system to detect cancer in patients undergoing surgery for endometrial cancer. The purpose of this study is to assess how well the investigational medication works when used with this imaging technique during surgery.Participants will undergo several …
This study investigates an investigational medication for people with advanced or metastatic malignant mesothelioma or other solid tumors. The purpose of this study is to evaluate the safety, tolerability, and early effectiveness of the investigational medication. The study is conducted in two parts: a dose escalation part to determine the …
The purpose of this study is to investigate the cancer risks linked to CTNNA1 gene alterations. CTNNA1 gene changes, known as loss-of-function variants, may increase the risk for certain hereditary cancers such as gastric and breast cancer. This study will collect personal and family history from individuals with these gene …
This study investigates the use of an investigational medication, epcoritamab, before and after CAR-T cell therapy in patients with relapsed or refractory large B-cell lymphomas. This study aims to understand if epcoritamab can improve outcomes when used in conjunction with CAR-T cell therapy, a treatment where a patient's T cells …
This study investigates head and neck squamous cell carcinoma (HNSCC). The purpose of this study is to understand the molecular characteristics of HNSCC by profiling biomarkers in tissue and blood samples from patients undergoing their usual care treatment.Participants in this study will have their tissue and blood samples collected for …
This study investigates the effectiveness of personalized mapping techniques for patients with Glioblastoma, a type of brain cancer. The purpose of this study is to compare two different mapping methods used in tumor treating fields (TTFields) therapy, which is a type of electrical therapy that has shown to improve survival …
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