Found 389 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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mNET is commonly treated with TACE or TACE. mNET cells can survive TACE or TARE ischemic conditions. In this study, we will biopsy mNETs being treated with TACE or TARE prior to treatment, after treatment, and again at recurrence to characterize the metabolic, immunologic, and genetic profile of the cells …
The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multi-site cohort of individuals with family history of PDAC and/or individuals carrying pathogenic/likely pathogenic germline variants (PGVs) in genes linked …
This study investigates the use of investigational medications following CAR T-cell therapy for individuals with relapsed or refractory large B-cell lymphoma and grade IIIB follicular lymphoma. The purpose of this study is to determine if additional treatment with investigational medications, after initial chemotherapy and CAR T-cell therapy, can better manage …
A single-dose, open-label, dose-escalation Phase 1b study in patients scheduled to undergo minimally invasive surgery (MIS) for known or suspected lung cancer via thoracoscopy (i.e., VATS). Single dose IV administration of Pemofolacianine for Injection, either on the day before surgery or on the day of surgery, with 2 different doses …
This study investigates the use of an investigational medication in comparison to primary surgery for individuals with early stage Cutaneous Squamous Cell Carcinoma (CSCC). This study aims to understand how the investigational medication affects the tumor and the body, as well as the potential side effects that may occur.Participants in …
This study investigates neuroendocrine tumors. It focuses on participants who have previously received treatment for tumors that cannot be removed by surgery or have spread to other parts of the body.This study evaluates the effectiveness of an investigational medication compared to everolimus. It examines how well the treatments work and …
This study investigates the effectiveness of an investigational medication following surgery and chemotherapy in patients with pancreatic cancer who have specific genetic mutations. The study focuses on patients whose cancer has been surgically removed and who have a mutation in the BRCA1, BRCA2, or PALB2 genes. These genes are known …
This study investigates the effects of an investigational medication targeting advanced or metastatic solid tumors, including sarcomas. The purpose of this research is to understand how the investigational medication, a recombinant humanized tetravalent antibody, interacts with the human death receptor 5 (DR5). The study aims to explore its potential therapeutic …
Colorectal cancer is amongst the top three leading causes of cancer and likewise, the third leading cause of cancer related mortality. In particular, there are limited therapeutic options for stage IV or metastatic CRC (to liver, lungs, and other sites), with 5-year survival being less than 10%. While preclinical model …
This study investigates whether additional regional nerve blocks can reduce pain and anxiety in adults undergoing Mohs micrographic surgery for skin cancers on the face and scalp. Participants will be randomly assigned to one of two study arms: one receiving a placebo nerve block with sterile saline and the other …
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