Found 352 oncology trials
A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The research study is being conducted to test an experimental vaccine to potentially prevent cancer for people with BRCA1 or BRCA2 mutations. This study will test if the vaccine is safe (without significant side effects) and test a new way of administering vaccines. It will also test whether the vaccine …
This research study is being conducted to evaluate experimental rescue therapies for the treatment of cytokine release syndrome (CRS) and CAR T cell related HLH-like syndrome (CRHLS). These are both life-threatening side effects which can occur in some patients after infusion with a CAR T cell product. This consent allows …
A Phase 2 study to evaluate the clinical activity, safety, and potentially predictive biomarker profile of ZN-c3 in subjects with High-Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
PURPOSE The overall objective is to demonstrate that the addition of ianalumab (either 3mg/kg or 9mg/kg dosage) to standard care (eltrombopag) is more effective and safer compared to the standard of care (eltrombopag) alone. Primary outcome variable is determined by the time to treatment failure which is in turn determined …
PURPOSE To evaluate the efficacy of ianalumab (i.e., platelet response 50 G/L) in participants with primary ITP previously treated with at least a corticosteroid and a TPO-RA. A platelet count of 50 G/L at two (or more) consecutive assessments at least 7 days apart between Week 1 Day 1 and …
To demonstrate that the addition of ianalumab to standard first-line corticosteroids prolongs Time to Treatment Failure compared to Corticosteroids alone in participants with primary ITP. ITP means immune thrombocytopenia. Time from randomization to treatment failure which is defined as Platelet count below 30G/L after 8 weeks from randomization. Need for …
To evaluate the efficacy of SPK-8011 in preventing bleed episodes compared with FVIII prophylaxis in patients with hemophilia A without FVIII inhibitors on routine FVIII prophylaxis. To evaluate the efficacy of SPK-8011 in preventing bleed episodes compared with FVIII prophylaxis in patients with hemophilia A without FVIII inhibitors on routine …
The primary objective of the present study is to evaluate the efficacy (effectiveness) of prophylactic (preventative doses) of emicizumab (FDA approved, also called Hemlibra) administered on a regular scheduled basis to prevent bleeds in patients with acquired hemophilia A (AHA). The secondary objectives are to study the safety of emicizumab …
Please see section 3 of the protocol for objectives and endpoints Please see section 3 of the protocol for objectives and endpoints Please see section 3 of the protocol for objectives and endpoints
To determine whether or not the 6D target is 0.5mm and 0.5deg for greater than 95% of treatment time using a robotic head holder. The primary study endpoint of the study is as follows: success will be defined as to whether or not the 6D intracranial target is 0.5mm and …
