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Found 389 oncology trials

A listing of oncology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years - 100 years
All genders
Phase 1/2
Interventional
This study investigates an investigational medication for adults with advanced MTAP-null solid tumors. The study aims to evaluate the safety and tolerability of the investigational medication alone and in combination with another treatment called docetaxel.Participants will receive the investigational medication orally, and their health will be monitored to assess the …
99 years or below
All genders
The overall objectives of this study focus on patients with either a personal or family history of gastrointestinal cancer, a hereditary gastrointestinal cancer susceptibility syndrome, and/or a gastrointestinal polyposis syndrome, and include: 1. Consent patients for genetic testing if genetic testing is deemed appropriate by the Cancer Risk Evaluation Program …
18 years - 99 years
All genders
To externally validate and refine prediction models for a) incident and b) subsequent KC in a prospective multi-center cohort of kidney and liver transplant recipients, with detailed data on UV exposure, skin type, and photosensitivity.
99 years or below
All genders
In this secondary use protocol, we will analyze de-identified data from a funded VA study called the Veterans Affairs Multi-omic Platform for Prostate Cancer (VA-MAPP) shared with our team through a fully executed data use agreement with the Greater Los Angeles VA and Penn Medicine to study the genetics of …
A Randomized, Open-Label, Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy
18 years - 100 years
Female
Phase 3
The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer …
UPCC 08220 Defining the Role of Germline Genetic Variants in Gastric Cancer Tumorigenesis
99 years or below
All genders
The research study is being conducted to better understand factors that lead to gastric (stomach) cancer, including differences in our genes that may put some people at increased risk of developing gastric cancer compared to other people. Both people with increased risk as well as people with average risk of …
18 years - 50 years
All genders
Phase 3
Interventional
This study investigates digital mindfulness-based interventions for younger breast cancer survivors who experience elevated depressive symptoms. The purpose of this study is to compare two different digital approaches: one that is live and instructor-led via Zoom, and another that is self-paced and app-based. Participants are breast cancer survivors diagnosed at …
18 years or above
All genders
Phase 3
Interventional
This study investigates the use of investigational medications for treating metastatic non-small cell lung cancer (mNSCLC) in patients whose tumors express PD-L1. The purpose of this study is to compare the effectiveness and safety of two treatments: one investigational medication and a standard treatment, pembrolizumab. Participants will be randomly assigned …
99 years or below
All genders
The objective of this consortium is to generate and utilize omics level data to elucidate the early steps in ovarian cancer (OvCa) initiation and provide the broader OvCa research community with a centralized resource of comprehensive omics datasets surveying the molecular landscapes of OvCa precursor lesions and their associated microenvironment. …
40 years or above
Accepts healthy volunteer
Male
This study investigates ways to detect prostate cancer earlier in people at genetic risk for aggressive disease, which forms, grows, or spreads quickly. The purpose is to study samples of blood, urine, and tissue in the laboratory to better understand the genetics of prostate cancer. This research aims to identify …
211 - 220 of 389