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Found 67 hematology trials
A listing of hematology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of polygenic risk scores (PRS) and novel early detection strategies in women at risk for ovarian cancer. The purpose of this study is to understand how women incorporate these tools in their decisions about cancer screening and risk-reducing surgery. Researchers will conduct qualitative interviews with …
The purpose of this study is to investigate how molecular changes in mature T-cell and NK-cell neoplasms affect patient outcomes like survival and treatment response. This study involves patients who are newly diagnosed or have relapsed/refractory forms of these cancers. An observational study is a type of research study where …
To receive genomic data from the GenPath lymphoma panel obtained from tumor samples from previously treated LBCL patients whose tumors have undergone NGS through a PCPD panel Receipt of a GenPath lymphoma panel report N/A
Investigate the involvement of the microbiome and associated metabolites in ovarian cancer. Generate a predictive model for ovarian cancer risk and progression. The primary outcome variable is metabolite identification and analysis. The secondary outcome variable is cancer risk as related to metabolites and genetic variants.
Determine if RAS Inhibitors inhibit the in vitro growth of RAS mutant primary human AML cells. This is a pre-clinical evaluation. There is only one outcome to be measured. The assay is a colony forming assay. AML cells form colonies which are manually counted. Endpoint will be a statistically significant …
The goal of the eREACH3 Study is to evaluate the implementation of digital tools into remote genetic services, evaluating uptake and use of digital tools and outcomes in representative clinical populations. Our primary endpoints will include uptake of services and digital alternatives (future amendments). We will use proportions and 95% …
This study investigates the use of a digital chatbot-enabled intervention compared to standard remote genetic services to increase the uptake of genetic counseling and testing among adolescents and young adult (AYA) cancer patients. Genetic testing helps identify cancer predisposition syndromes, which can guide enhanced screening and preventive measures. However, many …
The purpose of this study is to investigate the effect of adding an investigational medication to the immunotherapy drug durvalumab in patients with non-small cell lung cancer (NSCLC) who have undergone chemotherapy and surgery. The study aims to see if the combination of treatments can increase the time patients remain …
This study investigates the safety and effectiveness of an investigational medication combined with high-dose ifosfamide in treating children and adults with relapsed or refractory sarcomas. The investigational medication is known to inhibit certain proteins, such as MET and VEGFR2, which are involved in tumor growth. The purpose of the study …
This study investigates a targeted palliative care program for individuals with metastatic breast cancer and their caregivers. The aim of this study is to enhance communication between patients, caregivers, and clinicians about the patients' goals and preferences for care.Participants in the study will be randomly assigned to receive either the …
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