Found 67 hematology trials
A listing of hematology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of this study is to investigate primary immune thrombocytopenia. This study evaluates how well the investigational medication works with corticosteroids in maintaining platelet count in adults.The study focuses on assessing the safety and effectiveness of the investigational medication in comparison to a placebo. It evaluates how the treatment …
The aim of this study is to biobank blood and stool samples of healthy individuals receiving β-hydroxybutyrate (BHB) supplementation. Additionally, this study will determine whether BHB supplementation increases serum BHB levels and leads to changes in T cell phenotype, including composition (i.e. CD4/CD8), and cytokine secretion. BHB supplementation will be …
The primary objective is to assess the efficacy of mezagitamab compared with placebo in achieving durable platelet response in participants aged 18 years with chronic ITP. Durable platelet response through Week 24, defined as platelet count 50,000/uL on at least 4 of the 6 weekly platelet measurements between Week 19 …
To evaluate the long-term safety and tolerability of mezagitamab in participants 18 years of age with chronic primary ITP. To evaluate the long-term efficacy of mezagitamab in participants 18 years of age with chronic primary ITP. Occurrence of TEAEs and serious TEAEs. Occurrence of TEAEs leading to permanent withdrawal of …
To assess safety and tolerability, including dose-limiting toxicities (DLTs), maximum tolerated dose (MTD), or maximum administered dose (MAD; if no MTD is defined) of IMGN151 when administered intravenouslyTo determine recommended Phase 2 dose (RP2D) for IMGN151To characterize the pharmacokinetics (PK) and immunogenicity of IMGN151 -To assess ORR for IMGN151 using …
PhenoTA proposes an automated solution for T, B, and NK cells, as well as other cell enumeration, identification and conditions, leveraging Raman spectroscopy, instead of traditional immunophenotypic and morphologic evaluation. This innovation aligns with the growing demand for rapid, cost-effective immunophenotyping and has the potential to transform standard hematology practice …
This study investigates the effects of lower doses of cyclophosphamide, a chemotherapy drug, in patients undergoing bone marrow transplants for certain blood cancers. Blood cancers like leukemia and lymphoma can sometimes be treated with a transplant, but there is a risk that the transplanted cells will attack the recipient's body, …
This study investigates the safety and feasibility of using investigational medications as rescue therapies for conditions related to CAR T cell therapy, specifically cytokine release syndrome (CRS) and hemophagocytic lymphohistiocytosis-like syndrome (CRHLS). These conditions can occur after receiving CAR T cell therapy, which is a treatment that modifies a patient's …
This study investigates the safety and tolerability of an investigational medication for women with hormone receptor-positive (HR+) and human epidermal growth factor receptor 2 negative (HER2-) metastatic breast cancer. The study focuses on participants whose tumors have mutations in the PIK3CA gene. The purpose is to find the safest and …
This study investigates the use of CAR T cells, a type of cell therapy, in treating patients with CD19+ cancers. The purpose of this study is to understand how safe and feasible it is to use these modified cells in patients whose cancer has come back or has not responded …
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