Found 21 hematology trials
A listing of hematology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
PURPOSE The overall objective is to demonstrate that the addition of ianalumab (either 3mg/kg or 9mg/kg dosage) to standard care (eltrombopag) is more effective and safer compared to the standard of care (eltrombopag) alone. Primary outcome variable is determined by the time to treatment failure which is in turn determined …
PURPOSE To evaluate the efficacy of ianalumab (i.e., platelet response 50 G/L) in participants with primary ITP previously treated with at least a corticosteroid and a TPO-RA. A platelet count of 50 G/L at two (or more) consecutive assessments at least 7 days apart between Week 1 Day 1 and …
To demonstrate that the addition of ianalumab to standard first-line corticosteroids prolongs Time to Treatment Failure compared to Corticosteroids alone in participants with primary ITP. ITP means immune thrombocytopenia. Time from randomization to treatment failure which is defined as Platelet count below 30G/L after 8 weeks from randomization. Need for …
To evaluate the effects of VLX-1005 compared to placebo on platelet count recovery, an important clinical outcome in patients with positive serotonin release assay (SRA+) confirmed HIT, on a background of standard of care (SoC) anticoagulation -To evaluate the effects of VLX-1005 compared to placebo on platelet count recovery, an …
To evaluate the efficacy of SPK-8011 in preventing bleed episodes compared with FVIII prophylaxis in patients with hemophilia A without FVIII inhibitors on routine FVIII prophylaxis. To evaluate the efficacy of SPK-8011 in preventing bleed episodes compared with FVIII prophylaxis in patients with hemophilia A without FVIII inhibitors on routine …
Please refer to Protocol Section 2.1 (Objectives). Please refer to Protocol Section 2.2.1 (Primary Endpoints). Please refer to Protocol Section 2.2.2 (Secondary Endpoints).
The primary objective of the present study is to evaluate the efficacy (effectiveness) of prophylactic (preventative doses) of emicizumab (FDA approved, also called Hemlibra) administered on a regular scheduled basis to prevent bleeds in patients with acquired hemophilia A (AHA). The secondary objectives are to study the safety of emicizumab …
The purpose of this study is to compare the efficacy of teclistamab with PVd/Kd in multiple myeloma patients.
The goal of this prospective study is to evaluate the safety and effectiveness of the da Vinci Xi Surgical System, instruments, and accessories in Nipple Sparing Mastectomy, otherwise known as NSM procedures.
Observation Period: Primary objectives: To observe and characterize seizure frequency via study-specific electronic seizure diaries in adults with unilateral refractory MTLE. condary: -To observe and characterize electroencephalogram (EEG) via 48-hour EEG recording. -To observe and characterize patient-reported outcomes (PROs). B) Evaluation Period Primary: To evaluate the safety and tolerability of …
