Found 35 cardiology trials
A listing of cardiology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This is a prospective, multi-center, randomized, indication expansion investigational device exemption study. This study will look at the safety and effectiveness of left bundle branch area pacing (LBBAP) in patients with heart failure with reduced ejection fraction (HFrEF) and left bundle branch block (LBBB) with an indication for a cardiac …
The purpose of this study is to evaluate the efficacy and safety of concomitant use of eplontersen and ALXN2220 compared with eplontersen and placebo in adult participants with ATTR-CM who are treated with standard-of-care therapy as determined by the treating and study physician(s). The study duration will be up to …
Study AG10-404 is a single-arm, prospective, longitudinal, open-label study to investigate the long-term effects of acoramidis on improving cardiac function and structure, and on cardiac amyloid burden in participants with transthyretin amyloid cardiomyopathy (ATTR-CM) over 36 months using two well-established, complementary imaging modalities - cardiac echocardiography and cardiac magnetic resonance …
Open-label, multi-center, international, prospective, single-arm, study to obtain market approval for the LivIQ system. Patients with a class I or II indication for ventricular pacing (VVI/VDD), Bradycardia (slow heart rate) will be enrolled in the study. LivIQ VR-T DX is a leadless pacemaker, is an investigational device that can sense …
DPP4 is an enzyme that breaks down proteins that may affect blood sugar and the heart. We will recruit individuals from the Penn Biobank (cases, controls). Participants will be asked to complete a meal test, DXA, and echocardiogram with exercise. A cardiac MRI and related pilot study are optional.
This study will focus on fat buildup inside the heart muscle, a newly recognized factor that makes patients vulnerable to such fast heart rates, or ventricular tachycardia, after a heart attack. This work may identify more successful strategies for curing dangerously fast heart rates. Adult subjects with prior history of …
The REAL AF Registry is an observational, prospective, non-randomized registry designed to find out more about the outcomes for patients who receive an ablation as treatment for Paroxysmal Atrial Fibrillation (PAF) and Persistent (PsAF) Atrial Fibrillation. The registry aims to better understand real-world information for patients with this disorder. Eligible …
This research study seeks to validate how echocardiogram (echo) data predicts response to cardiac resynchronization therapy (CRT) provided by a CRT device with a defibrillator (CRT-D) in individuals without the heart arrhythmia abnormality left bundle branch block (LBBB). It also aims to identify new variables recorded from electrocardiograms (ECG) or …
THRIVE is an international, multicenter, 2:1 randomized, double blind, sham-controlled study, designed to demonstrate the adjunctive effectiveness and safety of the Therapeutic Intravascular Ultrasound (TIVUS) Renal Denervation System in hypertensive subjects while subjects are maintained off-antihypertensive medications for a 4-week wash-out period before RDN/Sham procedure and 2 months after procedure.
This is a prospective, multi-center, global, single-arm, pivotal investigational study designed to evaluate the safety and effectiveness of the CSP ICD Lead in a subject population indicated for ICD or CRT-D therapy.
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