Found 40 cardiology trials
A listing of cardiology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The REAL AF Registry is an observational, prospective, non-randomized registry designed to find out more about the outcomes for patients who receive an ablation as treatment for Paroxysmal Atrial Fibrillation (PAF) and Persistent (PsAF) Atrial Fibrillation. The registry aims to better understand real-world information for patients with this disorder. Eligible …
This research study seeks to validate how echocardiogram (echo) data predicts response to cardiac resynchronization therapy (CRT) provided by a CRT device with a defibrillator (CRT-D) in individuals without the heart arrhythmia abnormality left bundle branch block (LBBB). It also aims to identify new variables recorded from electrocardiograms (ECG) or …
THRIVE is an international, multicenter, 2:1 randomized, double blind, sham-controlled study, designed to demonstrate the adjunctive effectiveness and safety of the Therapeutic Intravascular Ultrasound (TIVUS) Renal Denervation System in hypertensive subjects while subjects are maintained off-antihypertensive medications for a 4-week wash-out period before RDN/Sham procedure and 2 months after procedure.
This is a prospective, multi-center, global, single-arm, pivotal investigational study designed to evaluate the safety and effectiveness of the CSP ICD Lead in a subject population indicated for ICD or CRT-D therapy.
The purpose of this study is to:Evaluate the efficacy of nucresiran compared to placebo on reducing all-cause mortality and cardiovascular (CV) eventsEvaluate the efficacy of nucresiran compared to placebo on additional assessments of CV events and/or deathEvaluate the efficacy of nucresiran compared to placebo on patient-reported health status and health-related …
This is an open-label, single arm, multicenter extension study for participants with established CVD and elevated Lp(a) who completed the parent study. The purpose of this study is to assess the long-term safety and tolerability of pelacarsen (TQJ230). The study consists of: Screening period (up to approximately 30 days) and …
The purpose of the study is to evaluate the safety and efficacy of dual chamber personalized pacing compared to minimal or no pacing for the treatment of HFpEF. This study will evaluate a personalized cardiac pacing rate as a treatment for symptomatic heart failure with preserved ejection fraction (LVEF ≥50%).
V-INTERVENTION will evaluate the effectiveness of inclisiran in preventing major cardiovascular and limb events in patients receiving percutaneous coronary or peripheral arterial revascularization. Inclisiran is a subcutaneous, twice-yearly injection that is FDA-approved as an add-on with statin therapy and on the market to lower LDL-C in high-risk populations.
This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced Ejection Fraction (HFmrEF) and excess body weight when compared to placebo.
This study investigates the effects of an investigational medication compared to other treatments chosen by doctors for adults with chronic lymphocytic leukemia (CLL) and moderate to severe heart problems. The study will include people whose heart function is below normal, as measured by a test called left ventricular ejection fraction …
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