Found 40 cardiology trials
A listing of cardiology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study aims to compare the outcomes of patients undergoing early surgical intervention for ascending aortic aneurysms to those undergoing aneurysm surveillance. Patients with aneurysm diameters between 5.0 and 5.4 cm will be randomized to receive either medical therapy or elective surgery and will be followed annually for 5 years. …
This is a prospective global multicenter long-term observational study designed to document the clinical outcomes of patients with hereditary transthyretin-mediated amyloidosis or wild-type transthyretin-mediated amyloidosis and the safety of patisiran (Onpattro) when used in patients with ATTRv amyloidosis. This is data collection study only and no study medication no visits …
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
This registry is a retrospective observational, multi-center study designed to collect data and analyze data retrospectively on patients with AL or TTR cardiac amyloidosis. Subjects under the care of the local investigator will be identified and consented. No patient visits or patient procedures will be required for the purpose of …
This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System plus anticoagulation compared to anticoagulation alone for intermediate-risk acute PE. Up to 1200 subjects with intermediate-risk acute PE will be randomized. All subjects who sign informed consent and who meet all of the inclusion criteria and none …
This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled, parallel group, event-driven, superiority, group sequential study to evaluate the efficacy and safety of milvexian in participants enrolled within 7 days of an Acute Coronary Syndrome. Participants will receive either milvexian/ placebo on a background of standard-of-care antiplatelet therapy. The total …
This is a prospective, multicenter,randomized, nonblinded study to evaluate the safety and effectiveness of the Aortix System versus standard of care medical therapy in patients hospitalized with ADHF and persistent congestion despite usual medical management and who are not being considered for nearterm advanced HF therapy (i.e., LVAD placement or …
The AMPLIFY EP Registry is an observational, prospective, multi-center, non-randomized registry designed to obtain real world clinical experience with the TactiFlex Catheter Ablation system in the treatment of Atrial Fibrillation. Patient assessments will occur at pre- procedure and procedure, and 1 year post ablation.
The study is a prospective, open-label, multicenter, extension study of acoramidis in participants with newly diagnosed ATTR-CM (or both ATTR-CM and ATTR-PN). The study population will be participants from the AG10-501 study only who are newly diagnosed with ATTR-CM (or both ATTR-CM and ATTR-PN) during that study. Participants will be …
This study investigates the occurrence of irregular heart rhythms in patients with chronic lymphocytic leukemia (CLL) who are treated with Bruton’s Tyrosine Kinase (BTK) inhibitors. The purpose of this study is to use wearable technology to monitor heart rhythms and blood pressure at home, aiming to understand how often patients …
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