Found 39 Leukemia trials
A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effects of an investigational medication in combination with chemotherapy for adults with newly diagnosed FLT3-ITD negative acute myeloid leukemia (AML). This trial will compare the investigational medication to a placebo to see if it improves overall survival in these patients.Participants will receive either the investigational medication …
This study investigates providing access to an investigational medication for patients with serious or life-threatening conditions where standard treatments are not suitable. The study focuses on patients with out-of-specification leukapheresis products or out-of-specification manufactured cells for treatment. Leukapheresis is a procedure that involves removing white blood cells from the body, …
This study investigates the safety and effectiveness of an investigational medication in patients with relapsed or refractory leukemias, including those with specific genetic changes such as MLL/KMT2A gene rearrangement or NPM1 mutation. The study is divided into two phases: Phase 1 aims to find the best dose of the investigational …
The purpose of this study is to provide access to an investigational treatment for adult patients with acute lymphoblastic leukemia (ALL). This study is focused on patients who have already had a procedure called leukapheresis, where blood cells are collected, and have had an investigational treatment made from their cells, …
The purpose of this study is to assess the retreatment of chronic lymphocytic leukemia (CLL) using a combination of investigational medications. Participants in this study have previously been treated with a specific therapy involving an anti-CD20 antibody and are now being evaluated for retreatment. The study will look into how …
This study investigates the effects of an investigational medication compared to other treatments chosen by doctors for adults with chronic lymphocytic leukemia (CLL) and moderate to severe heart problems. The study will include people whose heart function is below normal, as measured by a test called left ventricular ejection fraction …
This study investigates the occurrence of irregular heart rhythms in patients with chronic lymphocytic leukemia (CLL) who are treated with Bruton’s Tyrosine Kinase (BTK) inhibitors. The purpose of this study is to use wearable technology to monitor heart rhythms and blood pressure at home, aiming to understand how often patients …
This study investigates the long-term safety and effects of an investigational medication in people with Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), or Non-Hodgkin Lymphoma (NHL) who have already received treatment. The purpose of this study is to provide participants from a previous study with the opportunity to continue …
The purpose of this study is to investigate the long-term safety of an investigational medication after participants have completed earlier clinical studies. This study will include individuals from previous studies, called originator studies, and will allow them to continue receiving treatment or follow-up visits. The study will use a master …
This study investigates the safety and feasibility of using investigational cells called huCART19-IL18 in patients with relapsed or refractory CD19+ cancers. These are cancers where the CD19 protein is present on the surface of malignant cells, such as certain types of lymphoma and leukemia. The purpose is to determine if …
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