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Found 37 Leukemia trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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UPCC 33418 Managed Access Program (MAP) Cohort Treatment Plan CCTL019B2003I to Provide Access for Patients With Out of Specification Leukapheresis Product and/or Out of Specification Manufactured Tisagenlecleucel (CTL019; Kymriah®)
All genders
This study investigates providing access to an investigational medication for patients with serious or life-threatening conditions where standard treatments are not suitable. The study focuses on patients with out-of-specification leukapheresis products or out-of-specification manufactured cells for treatment. Leukapheresis is a procedure that involves removing white blood cells from the body, …
30 days or above
All genders
Phase 1/2
Interventional
This study investigates the safety and effectiveness of an investigational medication in patients with relapsed or refractory leukemias, including those with specific genetic changes such as MLL/KMT2A gene rearrangement or NPM1 mutation. The study is divided into two phases: Phase 1 aims to find the best dose of the investigational …
18 years or above
All genders
The purpose of this study is to provide access to an investigational treatment for adult patients with acute lymphoblastic leukemia (ALL). This study is focused on patients who have already had a procedure called leukapheresis, where blood cells are collected, and have had an investigational treatment made from their cells, …
18 years or above
All genders
Phase 2
Interventional
The purpose of this study is to assess the retreatment of chronic lymphocytic leukemia (CLL) using a combination of investigational medications. Participants in this study have previously been treated with a specific therapy involving an anti-CD20 antibody and are now being evaluated for retreatment. The study will look into how …
18 years - 130 years
All genders
Phase 4
Interventional
This study investigates the effects of an investigational medication compared to other treatments chosen by doctors for adults with chronic lymphocytic leukemia (CLL) and moderate to severe heart problems. The study will include people whose heart function is below normal, as measured by a test called left ventricular ejection fraction …
22 years or above
All genders
Observational
This study investigates the occurrence of irregular heart rhythms in patients with chronic lymphocytic leukemia (CLL) who are treated with Bruton’s Tyrosine Kinase (BTK) inhibitors. The purpose of this study is to use wearable technology to monitor heart rhythms and blood pressure at home, aiming to understand how often patients …
18 years or above
All genders
Phase 4
Interventional
This study investigates the long-term safety and effects of an investigational medication in people with Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), or Non-Hodgkin Lymphoma (NHL) who have already received treatment. The purpose of this study is to provide participants from a previous study with the opportunity to continue …
18 years or above
All genders
Phase 4
Interventional
The purpose of this study is to investigate the long-term safety of an investigational medication after participants have completed earlier clinical studies. This study will include individuals from previous studies, called originator studies, and will allow them to continue receiving treatment or follow-up visits. The study will use a master …
18 years - 100 years
All genders
Phase 1/2
Interventional
This study investigates the use of an investigational treatment, rapcabtagene autoleucel, for different types of blood cancers including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), diffuse large B-cell lymphoma (DLBCL), acute lymphoblastic leukemia (ALL), and high-risk large B-cell lymphoma (HR LBCL).The study consists of two phases. In Phase I, …
18 years - 120 years
Accepts healthy volunteer
All genders
This study investigates whether primary palliative care can serve as an alternative to specialty palliative care in improving the quality of life, symptoms, mood, coping, and end-of-life outcomes for patients with acute myeloid leukemia (AML). These patients face a sudden, life-threatening diagnosis requiring immediate hospitalization and treatment, which can cause …
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