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Found 39 Leukemia trials
A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates a potential treatment for Acute Myeloid Leukemia (AML). The purpose of this study is to explore the use of a modified stem cell transplant combined with engineered T cells, known as chimeric antigen receptor (CAR) T cells, to target and attack leukemia cells. CAR T cells are …
Managed Access Program (MAP) to provide access to CTL019, for acute lymphoblastic leukemia (ALL) or diffuse large b-cell lymphoma (DLBCL) patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for commercial release. The primary purpose of a MAP is to provide access to product. NA - …
This study investigates the safety and anti-cancer activity of an investigational medication in adults with advanced B-cell malignancies. These conditions include Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Diffuse Large B-cell Lymphoma (DLBCL), Mantle Cell Lymphoma (MCL), Waldenstrom Macroglobulinemia (WM), Marginal Zone Lymphoma (MZL), Follicular Lymphoma (FL), Primary Central …
This study investigates the use of unlicensed cryopreserved cord blood units (CBUs) for transplantation in pediatric and adult patients with hematologic malignancies and other conditions. The purpose of this study is to understand how well patients recover neutrophil levels, a type of white blood cell important for fighting infections, after …
This study investigates the use of an investigational therapy for patients who have been diagnosed with a condition approved for treatment with this therapy, but whose therapy does not meet commercial release criteria. The purpose is to provide access to this investigational treatment under specific conditions.Participants in this study will …
This study investigates hematologic malignancies. The purpose of this study is to assess the safety and feasibility of using autologous anti-CD45 CAR T cells in combination with CD45 base edited hematopoietic stem and progenitor cells.The study evaluates the effectiveness and safety of these treatments in patients who have relapsed or …
This study investigates how effective one year versus two years of maintenance therapy is for patients with advanced ovarian cancer that has BRCA1/2 mutations or is homologous recombination deficient (HRD+). The purpose is to compare the effects of using the investigational medication, olaparib, with or without an antiangiogenic agent, bevacizumab, …
This study investigates how genetic testing can guide cancer treatment choices for patients with advanced solid tumors. The purpose is to use the genetic information from patients' tumor cells to match them with investigational combination therapies that target specific genetic mutations. This approach aims to control tumor growth and improve …
This study investigates the long-term safety of investigational cell therapies in patients who have previously participated in Caribou-sponsored clinical studies, special access programs, or investigator-initiated trials (IITs). The purpose of this study is to observe patients over a period of up to 15 years after they have received their initial …
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