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Found 39 Leukemia trials
A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the safety and efficacy of an investigational medication, surovatamig, administered alone or with other anticancer agents in individuals with mature B-cell malignancies. This study is open-label, meaning both researchers and participants know what treatment is being administered. It includes three substudies, each focusing on different types of …
This study investigates the use of an investigational drug called ziftomenib in combination with standard treatments for patients with acute myeloid leukemia (AML). This study focuses on patients with specific genetic changes, such as NPM1 mutations or KMT2A rearrangements, and includes those who are newly diagnosed as well as those …
This study investigates the use of frailty assessments to predict outcomes for patients aged 60 years and older who are receiving treatments such as chemotherapy, CAR T-cell therapy, or allogeneic stem cell transplant for blood cancers. Frailty assessments help determine a patient's physical resilience and vulnerability, which may influence treatment …
This study investigates a treatment for patients with acute myeloid leukemia (AML) who are not eligible for bone marrow transplantation. The purpose of the study is to evaluate the safety and tolerability of an investigational medication given as maintenance therapy. Patients in this study have AML, which is a type …
This study investigates different treatment approaches for patients with high-risk acute myeloid leukemia (AML), a type of cancer that affects the blood and bone marrow. The study compares the standard treatment of cytarabine and daunorubicin, which are chemotherapy drugs that stop cancer cell growth, with several experimental regimens. These include …
This study investigates the use of an investigational medication in combination with standard therapies for patients with acute myeloid leukemia (AML) who have specific genetic mutations and have not yet received treatment. The purpose of this study is to assess the benefits and risks of adding the investigational medication to …
This study investigates a treatment for adults with acute myeloid leukemia (AML) that has not responded to previous treatment or has returned after treatment. The purpose of this research is to evaluate the effectiveness and safety of an investigational medication given with Cytarabine, compared to a placebo given with Cytarabine. …
This study investigates treatments for adults newly diagnosed with BCR-ABL-positive Acute Lymphoblastic Leukemia (ALL). The purpose of this study is to compare the effectiveness of a standard treatment involving chemotherapy, steroids, and a type of medicine called a tyrosine kinase inhibitor (TKI) with a treatment that adds another medicine called …
This study investigates the effects of a combination of investigational medications in patients newly diagnosed with secondary acute myeloid leukemia (AML) after previous exposure to hypomethylating agents. The purpose of this study is to understand how these investigational medications work together to treat AML.Participants in the study will receive a …
Featured study
We are looking for healthy volunteers to donate bone marrow for research purposes. The Stem Cell & Xenograft Core provides bone marrow to laboratories on Penn’s campus researching leukemia and other blood disorders
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