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Found 139 Neoplasm Metastasis trials
A listing of Neoplasm Metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Primary Objective To assess whether B.brilliant, a Novel Digital Breast Tomosynthesis System leads to better visualization of calcifications compared to standard wide-angle DBT imaging Secondary Objectives To evaluate the accuracy of NDBT B.brilliant for predicting the number of calcifications and extent of the calcification cluster(s) and morphology compared to standard …
Primary Objectives:To perform metabolic phenotyping of treatment naïve and recurrent GBM by multitracer [18F]Fluciclovine and 18F-FDG PET. Secondary Objectives:To compare uptake measures of 18F-Fluciclovine and 18F-FDG and MRI quantification of glutamate and lactate levels to tumor tissue laboratory assays (RNA seq and proteomics) of glutamine/glutamate, glucose, and lactate metabolism. To …
This study investigates the use of a medical device containing yttrium-90 for treating liver cancer, specifically Hepatocellular Carcinoma (HCC). The purpose of this study is to evaluate the safety and effectiveness of Eye90 microspheres, which deliver localized radiation therapy directly to liver tumors. This approach is used for patients whose …
The aims of this study are four-fold: (1) To determine if cholate clearance is related to underlying cardiovascular hemodynamics, specifically low CO, elevated CVP, desaturation as seen in the Fontan. (2) To characterize Fontan patients with elevated systemic HFR/portal HFR ratio. (3) To know whether cholate clearance is a reliable …
The purpose of this study is to provide access to an investigational treatment for adult patients with acute lymphoblastic leukemia (ALL). This study is focused on patients who have already had a procedure called leukapheresis, where blood cells are collected, and have had an investigational treatment made from their cells, …
We propose an iterative approach to develop and pilot test a new mHealth behavioral intervention for AET adherence that is culturally tailored to Black breast cancer survivors. We will first use qualitative methods informed by Black breast cancer survivors to develop a blueprint of the intervention (Aim 1). We will …
The primary objective of this study is to determine the level of regret patients experience following the decision to pursue amputation and how the extent of patient-reported regret varies with respect to indication (neoplasm versus trauma versus infection). Our secondary objective is to examine how patient- and surgeon-specific factors (including …
This study investigates the efficacy and safety of an investigational medication in combination with chemotherapy for treating individuals with metastatic HER2-positive breast cancer. Participants in this study have previously been treated with a specific medication called T-DXd but have either not responded or cannot tolerate it.Participants will be randomly assigned …
This study investigates the safety and anti-cancer activity of an investigational medication in adults with advanced B-cell malignancies. These conditions include Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Diffuse Large B-cell Lymphoma (DLBCL), Mantle Cell Lymphoma (MCL), Waldenstrom Macroglobulinemia (WM), Marginal Zone Lymphoma (MZL), Follicular Lymphoma (FL), Primary Central …
This study investigates the safety, tolerability, and anti-tumor activity of an investigational medication in adult patients with solid tumors that express MAGE-A4, a specific tumor-associated antigen. The study focuses on individuals with the HLA-A*02:01 tissue marker, which is necessary for participation.Participants will undergo various study procedures to evaluate the maximum …
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