Found 139 Neoplasm Metastasis trials
A listing of Neoplasm Metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
This study investigates how effective one year versus two years of maintenance therapy is for patients with advanced ovarian cancer that has BRCA1/2 mutations or is homologous recombination deficient (HRD+). The purpose is to compare the effects of using the investigational medication, olaparib, with or without an antiangiogenic agent, bevacizumab, …
This study investigates the effect of adding stereotactic body radiation therapy (SBRT) to the usual treatment for patients with locally advanced non-small cell lung cancer (NSCLC) that cannot be treated with surgery. The purpose is to see if SBRT, which uses precise radiation to target tumors, can improve outcomes when …
This study investigates the effects of an investigational medication, ORIC-114, on patients with advanced solid tumors that show changes in certain genes known as EGFR or HER2. The purpose of this study is to determine the best dose for Phase 2 trials and to evaluate the safety and effectiveness of …
This study investigates early-stage triple-negative breast cancer (TNBC) and the effects of observation versus continued immunotherapy after achieving a complete response to initial treatments. The study aims to determine if observation alone can provide similar outcomes to further treatment with an investigational medication after surgery.Participants will be divided into two …
This study investigates PARP-1 expression in men with metastatic prostate cancer using a special imaging technique called PET/CT scans. The purpose of this study is to observe how a radiotracer, which is a substance used to highlight areas of the body in imaging tests, interacts with cancerous sites in the …
This study investigates the impact of empathic communication skills training on reducing perceived stigma in lung cancer patients. Lung cancer patients often feel stigma during medical encounters, which can affect their well-being and the quality of care they receive. The purpose of this study is to evaluate whether training oncology …
This study investigates the use of a digital chatbot-enabled intervention compared to standard remote genetic services to increase the uptake of genetic counseling and testing among adolescents and young adult (AYA) cancer patients. Genetic testing helps identify cancer predisposition syndromes, which can guide enhanced screening and preventive measures. However, many …
The TMD-PRIME study will be a repository for DNA, RNA, plasma, serum, bone, & tissue from patients enrolled at the Penn Center for Temporomandibular Joint Disease (TMD). TMD-PRIME will create a bio-specimen & data repository by integrating efforts of researchers focused on the study of causes, detection, treatment, & prevention …
This study investigates two different ways to manage lymphedema in individuals who have survived head and neck cancer. This study compares clinic-based Complete Decongestive Therapy (CDT) with a home-based hybrid model of CDT to see how each approach affects the severity of lymphedema in participants.Participants will either receive CDT in …
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