Found 139 Neoplasm Metastasis trials
A listing of Neoplasm Metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The objectives of the study are to recruit patients with tumors of the autonomic nervous system and develop an annotated database including tissue samples to facilitate research with the goal of better understanding the genetics and biochemical signaling pathways leading to tumor formation and malignancy. The primary goal of this …
Phase 2: To evaluate BICR-assessed objective response rate at each dose level of R-DXd. Phase 3:To evaluate BICR-assessed objective response rate with R-DXd treatment compared with investigator's choice of paclitaxel, PLD, gemcitabine, or topotecan. Objectives, outcome measures, and endpoints are located in Tables 3.1 and 3.2 of the protocol. Phase …
This study investigates different dosing strategies for CDK4/6 inhibitors in older patients with metastatic breast cancer (MBC). The purpose of the study is to compare standard dosing with a titrated dosing approach to see which helps patients tolerate the medication better and continue treatment longer.Participants will be randomly assigned to …
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The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guidelines at the point of care, leading to substantial under-utilization. …
This study investigates the genetic risk in young adults with cancer and their relatives. The purpose is to understand how universal genetic testing can identify individuals with a higher risk of cancer who might be missed by traditional testing methods. This study involves young adult cancer patients, aged 18 to …
The objective of this study is to show that inhaled nitric oxide can increase blood flow in the brain after traumatic brain injury, attenuating brain injury and resulting in improved long-term function. We will use optical brain monitoring to determine changes in cerebral perfusion and metabolism by iNO treatment in …
The objective of this study is to obtain neural recordings from deep brain structures while performing simple intraoperative tasks in order to improve the understanding of temporal relationship of deep neural signals and the performance of simple psychomotor, cognitive, and/or executive tasks. The standard DBS surgery provides an opportunity to …
Primary: Determine if influenza infection elicits antibodies that bind to and neutralize older influenza virus strains. Secondary: Characterize B cell and T cell responses to influenza virus infection. Specificity, quantity, and quality of serum antibodies to influenza viruses using assays including but not limited to FRNT, ELISA, ELLA, and HAI. …
This study's primary objective will be to collect tissue & body fluid specimens for immediate analysis and short term storage, to obtain scientifically relevant clinical characteristics, and to maintain patient confidentiality in patients undergoing Thoracic Surgery at the Hospital of the University of Pennsylvania. To examine and identify cell markers …
To determine the effect of provider contact on clinically-indicated follow-up for imaging findings potentially representing cancer. Our primary variable is 1) rates of clinically indicated imaging and pathology follow-up completed within recommended time interval, before contacting the provider and 2) rates of clinically-indicated follow-up completed after the recommended time interval, …
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