Found 139 Neoplasm Metastasis trials
A listing of Neoplasm Metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Sort by:
This study investigates the safety and effectiveness of an investigational treatment for patients with metastatic triple-negative breast cancer (TNBC) that is PD-L1-negative. The purpose of this study is to evaluate Sacituzumab Govitecan, alone or in combination with Pembrolizumab, in delaying the progression of this cancer.Participants will undergo various study procedures, …
This study investigates an investigational medication for patients with HER2-positive metastatic breast cancer. The purpose of this study is to evaluate the effects of this investigational medication in patients who have previously been treated with a specific therapy called T-DXd.Participants in this study will receive the investigational medication through an …
This study investigates the effectiveness of a quantitative HER2 assay in distinguishing between patients with HER2 IHC1+ metastatic breast cancer who respond to treatment and those who do not. The purpose is to determine if this assay can reliably identify patients who are likely to benefit from receiving investigational medications …
This study investigates the effectiveness of adding enhanced therapy to standard treatment for prostate cancer patients experiencing biochemical recurrence. The study aims to compare standard prostate radiation therapy combined with short-term androgen deprivation to an enhanced therapy regimen that includes additional medications. Another aspect of the study examines the use …
This study investigates the treatment of patients with unresectable metastatic neuroendocrine tumors (NETs) that are primarily located in the liver. The purpose of this study is to evaluate the effectiveness and safety of a combination treatment using Capecitabine-Temozolomide (CapTem) and yttrium-90 (Y90) radioembolization.Participants in the study will receive CapTem, which …
This study investigates the safety and effectiveness of an investigational medication, either alone or with standard cancer treatments, in patients with advanced solid tumors, including urothelial cancer, that have a change in the FGFR3 gene. The purpose of this study is to learn more about how the investigational medication works …
Primary Objective: To determine changes in neurodegeneration over the first year of treatment with anti-amyloid monoclonal antibodies Secondary Objectives: To identify measures that detect and monitor neuroinflammation during anti-amyloid treatment. To explore the interaction between neuroinflammation and neurodegeneration Primary Endpoint: Neuroimaging and blood-based measures of neurodegeneration, cognitive performance Secondary Endpoints: …
3 OBJECTIVES AND ENDPOINTSPrimary and secondary outcomes will be assessed using routinely collected electronic health record data at Penn Medicine Princeton Medical Center, Pennsylvania Hospital, and Penn Medicine Lancaster General Hospital. Exploratory outcomes will be assessed among those consenting to correlative analyses using additional data collected from participant step count …
This study investigates hematopoietic cell transplantation and other cellular therapies, as well as marrow toxic injuries. The purpose is to collect observational data to better understand these conditions.The study will gather data from participants who undergo routine care, without altering their treatments. This observational study aims to create a comprehensive …
Investigate the involvement of the microbiome and associated metabolites in ovarian cancer. Generate a predictive model for ovarian cancer risk and progression. The primary outcome variable is metabolite identification and analysis. The secondary outcome variable is cancer risk as related to metabolites and genetic variants.
Please choose between Voice or SMS based delivery of verification code
or