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Found 139 Neoplasm Metastasis trials

A listing of Neoplasm Metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years - 120 years
Female
Phase 3
Interventional
This study investigates the effectiveness of letrozole, an investigational medication, in comparison to a placebo for postmenopausal women with hormone receptor-positive breast cancer. The purpose of this study is to determine if taking letrozole for five years can improve disease-free survival after completing five years of hormonal therapy, which may …
18 years or above
All genders
Interventional
This study investigates pancreatic cancer. It focuses on a structured lipid medical food designed to address fat malabsorption in patients who have difficulty absorbing fats due to their condition.The purpose of this study is to evaluate the safety, tolerance, and potential effects of the structured lipid medical food. It looks …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of adding an investigational medication to the standard treatment for patients with metastatic pancreatic cancer who have specific genetic mutations known as BRCA1 or BRCA2. The purpose of this study is to see if the combination of an investigational medication with olaparib, a targeted therapy …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effects of two investigational treatments for patients with differentiated thyroid cancer that does not respond to standard treatment and has a specific genetic change called BRAF V600E mutation. The purpose of this study is to compare the effectiveness and safety of cabozantinib, a receptor tyrosine kinase …
18 years or above
All genders
Phase 3
Interventional
The purpose of this study is to investigate the effect of adding an investigational medication to the immunotherapy drug durvalumab in patients with non-small cell lung cancer (NSCLC) who have undergone chemotherapy and surgery. The study aims to see if the combination of treatments can increase the time patients remain …
18 years or above
All genders
Phase 2
Interventional
This study investigates progressive meningiomas. It looks at how certain investigational medications work for people with this condition.The focus is on evaluating the safety and effectiveness of these investigational medications. The study will see how these medications impact the condition in general.Who can participate: Adults with progressive or residual meningiomas …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of interstitial photodynamic therapy (I-PDT) following palliative radiotherapy in patients with inoperable malignant central airway obstruction. The purpose of this study is to test the safety and effectiveness of combining these treatments to improve tumor response and survival in patients whose airways are blocked by …
35 years - 50 years
Female
Interventional
This study investigates the effectiveness of two surgical procedures in reducing the risk of ovarian cancer in individuals with BRCA1 mutations. The purpose of this study is to compare bilateral salpingectomy, which involves removing the fallopian tubes, with bilateral salpingo-oophorectomy, which involves removing both the fallopian tubes and ovaries. These …
EA2192 APOLLO: A Randomized Phase II Double-Blind Study of Olaparib versus Placebo Following Curative Intent Therapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of an investigational medication following surgery and chemotherapy in patients with pancreatic cancer who have specific genetic mutations. The study focuses on patients whose cancer has been surgically removed and who have a mutation in the BRCA1, BRCA2, or PALB2 genes. These genes are known …
18 years or above
All genders
Phase 3
Interventional
This study investigates the effectiveness of combining hormone therapy with or without an investigational medication in treating patients with breast cancer. Hormone therapies like tamoxifen citrate and others work by lowering estrogen levels, potentially slowing or stopping cancer growth. The investigational medication being studied may also stop tumor growth by …
121 - 130 of 139