Found 492 Barrett's Esophagus trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the use of an investigational medication in combination with standard therapies for patients with acute myeloid leukemia (AML) who have specific genetic mutations and have not yet received treatment. The purpose of this study is to assess the benefits and risks of adding the investigational medication to …
This study investigates the safety and feasibility of using T-cell receptor engineered donor T-cells in patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or acute lymphoblastic leukemia (ALL) who receive transplants from specific types of donors. The …
This study investigates the effectiveness of investigational medications for patients with advanced breast cancer who have specific genetic mutations. The purpose of this study is to compare the effects of saruparib plus camizestrant with other treatments chosen by the physician, including CDK4/6 inhibitors and endocrine therapy. The study focuses on …
This study investigates an investigational medication for people with advanced cancers that are positive for the PRAME protein. The study aims to understand the safety and effectiveness of this investigational medication in adults who have a specific genetic marker called HLA-A*02:01 and PRAME-positive tumors.Participants in this study will receive the …
This study investigates the safety and feasibility of using investigational medications as rescue therapies for conditions related to CAR T cell therapy, specifically cytokine release syndrome (CRS) and hemophagocytic lymphohistiocytosis-like syndrome (CRHLS). These conditions can occur after receiving CAR T cell therapy, which is a treatment that modifies a patient's …
V-INTERVENTION will evaluate the effectiveness of inclisiran in preventing major cardiovascular and limb events in patients receiving percutaneous coronary or peripheral arterial revascularization. Inclisiran is a subcutaneous, twice-yearly injection that is FDA-approved as an add-on with statin therapy and on the market to lower LDL-C in high-risk populations.
This study investigates the effects of an investigational medication on patients with relapsed and refractory multiple myeloma (RRMM). The purpose of the study is to evaluate the safety and effects of a selective inhibitor that targets a specific enzyme involved in the disease process.Participants will undergo a dose-escalation phase to …
This study aims to learn more about the use of Mirvetuximab soravtansine and Olaparib as a maintenance therapy after completion of prior therapy for recurrent platinum sensitive ovarian, peritoneal and fallopian tube cancer. Mirvetuximab soravtansine is an effective antibody drug conjugate that targets folate receptor alpha. Olaparib is one of …
The purpose of this study is to investigate the cancer risks linked to CTNNA1 gene alterations. CTNNA1 gene changes, known as loss-of-function variants, may increase the risk for certain hereditary cancers such as gastric and breast cancer. This study will collect personal and family history from individuals with these gene …
This study investigates the effectiveness of a combination of investigational medications in treating ovarian cancer associated with ARID1A mutation. The purpose of this study is to evaluate how well the combination of these medications works against tumors in patients with recurrent or persistent clear cell or endometrioid ovarian cancer, which …
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