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Found 492 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Phase 1/2
Interventional
This study investigates the safety and tolerability of genetically modified autologous T cells in patients with recurrent or refractory solid tumors. The T cells are engineered to express a receptor that recognizes a specific cancer-related protein called PRAME, which is often found in melanoma and other solid tumors. The study …
UPCC 21920 Randomized Trial of Universal vs. Guideline-Directed Germline Testing Among Young Adults with Cancer
18 years - 40 years
All genders
Interventional
The overarching goal of our research is to define an evidence-based, sustainable approach to identifying and managing genetic risk among young adults with cancer and their relatives. Conventional practice leaves referral and testing decisions to mostly non-expert clinicians implementing complex guidelines at the point of care, leading to substantial under-utilization. …
18 years - 40 years
All genders
Interventional
This study investigates the genetic risk in young adults with cancer and their relatives. The purpose is to understand how universal genetic testing can identify individuals with a higher risk of cancer who might be missed by traditional testing methods. This study involves young adult cancer patients, aged 18 to …
Identification of neoantigen-specific T cell responses in cancer patients within the Penn Medicine BioBank
18 years - 90 years
All genders
You are being asked to participate in this research investigation because you have expressed an interest in participating in a study to better understand how the immune cells of the body recognize and fight cancer.
18 years - 100 years
Accepts healthy volunteer
All genders
We are looking for healthy volunteers to donate bone marrow for research purposes. The Stem Cell & Xenograft Core provides bone marrow to laboratories on Penn’s campus researching leukemia and other blood disorders
18 years or above
All genders
The purpose of this study includes the following: ·         To test the efficacy and safety of the Study Drug and to find out what effects, good and/or bad, it has on you and your cancer. ·         To understand how the body absorbs and processes the Study Drug by measuring the …
18 years or above
Female
Interventional
This study investigates an imaging technique using an investigational medication and a special camera system to detect cancer in patients undergoing surgery for endometrial cancer. The purpose of this study is to assess how well the investigational medication works when used with this imaging technique during surgery.Participants will undergo several …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the use of a radiation boost in combination with immune checkpoint blockade therapy in patients with operable breast cancer. The purpose is to determine if combining pembrolizumab, an immune therapy, with a single radiation boost is feasible and effective. The study will track changes in tumor size …
18 years - 80 years
All genders
Phase 2/3
Interventional
This study investigates a treatment for adults with acute myeloid leukemia (AML) that has not responded to previous treatment or has returned after treatment. The purpose of this research is to evaluate the effectiveness and safety of an investigational medication given with Cytarabine, compared to a placebo given with Cytarabine. …
18 years or above
All genders
Phase 1
Interventional
This study investigates treatment options for individuals with recurrent or progressive IDH-1 mutant glioma, a type of brain tumor. The purpose is to evaluate the safety and effects of combining an investigational medication with another treatment. Participants will be divided into two phases: a Safety Lead-In phase to determine safe …
391 - 400 of 492