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Found 492 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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18 years or above
All genders
Observational
The purpose of this study is to investigate the long-term safety of a type of treatment called CAR T cell therapy. This study focuses on monitoring the long-term risks associated with this therapy, such as delayed adverse events and the persistence of modified T cells in the body.Participants in this …
Autologous orthotopic transplantation of previously cryopreserved ovarian tissue
18 years - 45 years
Female
Interventional
The purpose of this pilot study is to determine how safe, effective and acceptable it is to transplant previously frozen ovarian tissue in women who have infertility or inadequate hormonal function after chemotherapy or radiation. This procedure is experimental and may or may not help you achieve pregnancy or restore …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety of combining immunotherapy and radiation therapy for treating urothelial bladder cancer. The purpose of this study is to determine if it is safe to use both treatments at the same time, which is not the usual approach. Safety will be assessed based on any acute …
18 years or above
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational oral medication designed to degrade SMARCA2 in patients with advanced or metastatic solid tumors that have a SMARCA4 mutation. The purpose of this study is to understand how the investigational medication affects the body, how it is processed by the …
18 years - 120 years
Accepts healthy volunteer
All genders
This study investigates whether primary palliative care can serve as an alternative to specialty palliative care in improving the quality of life, symptoms, mood, coping, and end-of-life outcomes for patients with acute myeloid leukemia (AML). These patients face a sudden, life-threatening diagnosis requiring immediate hospitalization and treatment, which can cause …
18 years or above
All genders
Phase 1/2
Interventional
This study investigates the effects of an investigational medication, ORIC-114, on patients with advanced solid tumors that show changes in certain genes known as EGFR or HER2. The purpose of this study is to determine the best dose for Phase 2 trials and to evaluate the safety and effectiveness of …
18 years - 130 years
All genders
Observational
The purpose of this study is to investigate the effectiveness of an investigational medication in patients with HER2-positive solid tumors that are locally advanced, unresectable, or metastatic. In this study, HER2-positive is identified as IHC 3+. The study focuses on patients who have previously received systemic treatment for their condition …
5 years - 40 years
All genders
Phase 1
Interventional
This study investigates the safety and effectiveness of an investigational medication combined with high-dose ifosfamide in treating children and adults with relapsed or refractory sarcomas. The investigational medication is known to inhibit certain proteins, such as MET and VEGFR2, which are involved in tumor growth. The purpose of the study …
18 years or above
All genders
Phase 2
Interventional
This study investigates the effectiveness of different treatment combinations for Stage I HER2-positive breast cancer. The purpose of this study is to compare the side effects and long-term benefits of two different HER2-directed therapies used after surgery. Participants will be randomly assigned to one of two study arms: one receiving …
18 years - 70 years
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication in combination with chemotherapy for adults with newly diagnosed FLT3-ITD negative acute myeloid leukemia (AML). This trial will compare the investigational medication to a placebo to see if it improves overall survival in these patients.Participants will receive either the investigational medication …
441 - 450 of 492