Found 492 Barrett's Esophagus trials
A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
DPP4 is an enzyme that breaks down proteins that may affect blood sugar and the heart. We will recruit individuals from the Penn Biobank (cases, controls). Participants will be asked to complete a meal test, DXA, and echocardiogram with exercise. A cardiac MRI and related pilot study are optional.
This study investigates the effects of a combination of investigational medication and PD-1 inhibition on recurrent IDH-mutant glioma, a type of brain tumor. The purpose of this study is to see if this combination can stimulate an immune response against the tumor.Participants in this study will undergo different procedures depending …
Create a foundational resource for conducting and sharing ATN imaging and blood biomarker results in the context of the large clinically heterogenous brain-donor-enrolled multi-ADRC cohort. These imaging-plasma sets will be intrinsically linked to cognitive and neurobehavioral data collection, genetics and eventually neuropathology.
The present trial will evaluate safety, efficacy, PK, and immunogenicity of repeat dosing of spesolimab 900 mg i.v. vs. placebo, both in combination with oral corticosteroid (20 mg/day prednisone or prednisolone, which will be tapered off by Week 8) in trial participants with ulcerative PG.
Hydrocephalus is a medical condition in which an abnormal buildup of cerebrospinal fluid (CSF) causes the fluid-filled spaces of the brain, the ventricles, to become enlarged. Enlarged ventricles and increased intracranial pressure can cause headaches, dizziness, blurred vision, cognitive impairment, gait disturbances and in severe cases even brain herniation or …
Phase 2: To evaluate BICR-assessed objective response rate at each dose level of R-DXd. Phase 3:To evaluate BICR-assessed objective response rate with R-DXd treatment compared with investigator's choice of paclitaxel, PLD, gemcitabine, or topotecan. Objectives, outcome measures, and endpoints are located in Tables 3.1 and 3.2 of the protocol. Phase …
The purpose of this study is to assess the safety and effectiveness of a combination of investigational medication and another drug in treating advanced-stage ovarian, fallopian tube, or primary peritoneal cancer. This study targets cancers that express a specific protein called folate receptor alpha (FRα). This protein is found on …
The purpose of this research study is to collect clinical information and biologic specimens from patients receiving CAR T cells and other cancer immunotherapies. The clinical information and biologic specimens will be used to better understand how these therapies work to treat cancer and how they affect patients immune systems.
The aim is to prospectively evaluate the efficacy and mechanism of benefit of HI-CRT vs. BIV CRT in patients with Right Bundle Brank Block (RBBB). Left Ventricular Ejection Fraction (LVEF) will be assess at 6 months following HIS CRT Vs. BIV CRT implant in Heart Failure patients with RBBB.
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