A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Reliance Agreement requested with VUMC (IREx). Creation of an observational phenotyping cohort of patients with acute respiratory distress syndrome, pneumonia or sepsis. Clinical risk factors, molecular phenotypes, and illness trajectories during the acute and recovery phases of these critical illness syndromes to be assessed. Alteration protocol describes the minimal risk …
This phase 3, partially masked, randomized, multicenter study will include 2 periods: an Active Run-in Period (ie, Screening) and an Assessment Period. Participants who receive RGX-314 will be provided the opportunity to enroll into a long-term follow-up (LTFU) study (RGX-314-5101) after completion of or early discontinuation from this current study …
This study will evaluate HD nusinersen in participants previously treated with risdiplam who may not be receiving the optimal benefit from treatment because they have reached the dose ceiling of 5 mg.This Phase 3b, open-label, single-arm, interventional study will evaluate the efficacy and safety of HD nusinersen in nonambulatory participants …
This is a Phase Ib/II study in participants with advanced liver cancers. Cohort 1 - participants with locally advanced or metastatic hepatocellular carcinoma (HCC) who have not received prior systemic therapy for their disease. Participants who experience loss of clinical benefit or unacceptable toxicity during Stage 1 may be eligible …
The research study is being conducted to collect blood specimens to evaluate a new diagnostic blood test that will help physicians diagnose individuals that may have new symptoms of heart failure or to determine the severity in those with heart failure. Samples will be used to evaluate the usefulness and …
The EA7222 study is a randomized phase 3 trial of doxorubicin alone or in combination with pembrolizumab in patients with advanced UPS and related poorly differentiated sarcomas that cannot be removed by surgery (unresectable). The studys primary objective is to assess whether the combination therapy will improve PFS for this …
To assess TMS-EEG abilities to aid in diagnosis, prognosis, and classification of TBI patients and predictions of clinical outcomes as well as to assess Delphi-MD abilities in the classification of TBI injury in comparison to standard brain measures. Differentiating between healthy controls and TBI participants in measured outputs of the …
The purpose of this study is to determine if the combination of the three anti-cancer drugs carboplatin, paclitaxel, and ramucirumab is helpful in shrinking tumors or delaying tumor growth in participants with non-small cell lung cancer. This study will also assess whether it is safe to combine these drugs.Participants for …
This post-approval study will collect safety, performance, effectiveness, and neck dilatation data on Alto Abdominal Stent Graft System for the endovascular treatment of infrarenal abdominal aortic aneurysms and evaluate real-world outcomes in comparison to commercially available comparator devices. Penn Medicine patients with the Alto Abdominal Stent Graft System, a device …
The purpose of this study is to test the study drug, PC14586 alone and in combination with pembrolizumab in patients with an advanced solid tumor with a TP53 Y220C alteration who have gone through one or more anticancer therapies and are not responding. PC14586 will be tested at different doses …