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Found 376 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 PARP Inhibitor Niraparib in Combination with Trastuzumab in Patients with Metastatic HER2+ Breast Cancer
18-99 years
Female
Phase 1
Interventional
The HER2 regulates cell growth and survival. This study will evaluate a new treatment using a potent Poly polymerase (PARP) inhibitor known as Niraparib. Niraparib will be combined with trastuzumab, a HER2-targeted agent, to evaluate the safety and tolerability in patients with metastatic HER2 positive breast cancer. It is anticipated …
99 years and younger
All genders
Study is enrolling IgAN patients who continue to have persistent proteinuria despite being on RAAS inhibitors for at least 12 weeks. The study intervention is subcutaneous atacicept given once a week. Interested subjects will be taking study drug for up to 96 weeks (36 weeks blinded + 60 weeks open …
99 years and younger
All genders
Subjects currently enrolled in the PD0053 can be enrolled in this study. Subjects will take UCB0599 capsules twice a day at either 180 mg or 360 mg approximately 12 hours apart. The start of the study will overlap with the end of the parent study and run for 30 months …
99 years and younger
All genders
To determine if overall survival (OS) is improved with proton beam therapy (PBT) treatment as compared to intensity modulated radiation therapy (IMRT) as part of planned protocol treatment for patients with esophageal cancer. To determine if OS with PBT is non-inferior to IMRT as part of planned protocol treatment and …
99 years and younger
All genders
ATSN-201 is a gene therapy designed to introduce the functional hRS1 gene to photoreceptors in the eye via subretinal admin using a novel rAAV vector, thereby restoring or attenuating the deterioration of vision in patients with XLRS. Subretinally administered AAV vector-mediated gene augmentation therapy has been shown to be safe …
 TAMBE- Evaluation of the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis in the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
18-99 years
All genders
Normal 0 false false false EN-US JA X-NONE Patients with thoracoabdominal or pararenal aneurysm disease will be asked to take part in this research study This research study will look at treating thoracoabdominal or pararenal aneurysm disease with a new stent-graft design. The reason we are doing this research study …
99 years and younger
All genders
Primary: To determine the preliminary efficacy of TATE in the locoregional treatment of NET liver metastases using ORR based on Response Evaluation Criteria in Solid Tumors (RECIST) criteria 1.1 and the DoR. Secondary: Determine the toxicity of TATE in NET patients with liver-dominant metastases Determine the PFS by mRECIST and …
99 years and younger
All genders
This study is for patients who have NCFBE who also have comorbid P aeruginosa infections. This study is testing AP-PA02 as a possible treatment for these infections and consists of 5 phages. The study includes physicals, infectious disease blood tests, ECGs, HRCT, blood and urine safety labs and phage labs …
99 years and younger
All genders
The purpose of this study is to learn how participant factors (such as medical history and manufacturing starting material, also known as Apheresis) can predict successful manufacturing of ciltacabtagene autoleucel (Cilta-cel). This information can be used to potentially improve manufacturing processes and treat more patients with Cilta-cel. We would like …
99 years and younger
All genders
A Reliance Agreement with Beth Israel Deaconess Medical Center is requested (SMART IRB). Improved mechanical ventilation treatment strategies are needed to improve outcomes in ICU patients with acute respiratory distress syndrome (ARDS). This study compares standard mechanical ventilation to a lung-stress oriented ventilation strategy in patients with ARDS. Personalized, precision …
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