Found 136 Lymphocytic Leukemia, Acute trials
A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Study is designed to evaluate the efficacy and safety of brenipatide in adults with moderate-to-severe alcohol use disorder (AUD). This study will investigate the effects of brenipatide across a wide dose range to inform further clinical development of the molecule for the treatment of AUD.
This study investigates the safety and feasibility of using T-cell receptor engineered donor T-cells in patients undergoing allogeneic peripheral blood stem cell transplantation. The study focuses on patients with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or acute lymphoblastic leukemia (ALL) who receive transplants from specific types of donors. The …
The purpose of this study is to provide access to an investigational treatment for adult patients with acute lymphoblastic leukemia (ALL). This study is focused on patients who have already had a procedure called leukapheresis, where blood cells are collected, and have had an investigational treatment made from their cells, …
This study investigates treatments for adults newly diagnosed with BCR-ABL-positive Acute Lymphoblastic Leukemia (ALL). The purpose of this study is to compare the effectiveness of a standard treatment involving chemotherapy, steroids, and a type of medicine called a tyrosine kinase inhibitor (TKI) with a treatment that adds another medicine called …
This study investigates the safety and effectiveness of an investigational medication in patients with relapsed or refractory leukemias, including those with specific genetic changes such as MLL/KMT2A gene rearrangement or NPM1 mutation. The study is divided into two phases: Phase 1 aims to find the best dose of the investigational …
Managed Access Program (MAP) to provide access to CTL019, for acute lymphoblastic leukemia (ALL) or diffuse large b-cell lymphoma (DLBCL) patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for commercial release. The primary purpose of a MAP is to provide access to product. NA - …
This study investigates the use of an investigational treatment, rapcabtagene autoleucel, for different types of blood cancers including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), diffuse large B-cell lymphoma (DLBCL), acute lymphoblastic leukemia (ALL), and high-risk large B-cell lymphoma (HR LBCL).The study consists of two phases. In Phase I, …
This study investigates the safety and feasibility of using investigational cells called huCART19-IL18 in patients with relapsed or refractory CD19+ cancers. These are cancers where the CD19 protein is present on the surface of malignant cells, such as certain types of lymphoma and leukemia. The purpose is to determine if …
This study investigates providing access to an investigational medication for patients with serious or life-threatening conditions where standard treatments are not suitable. The study focuses on patients with out-of-specification leukapheresis products or out-of-specification manufactured cells for treatment. Leukapheresis is a procedure that involves removing white blood cells from the body, …
This study investigates the long-term safety and efficacy of gene-modified T-cell therapy in both children and adults. The purpose is to observe participants who have previously received this therapy in a Celgene or Celgene alliance partner study.Participants will be monitored over time to assess the effects of the gene-modified T …
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