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Found 74 Lymphocytic Leukemia, Acute trials

A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Managed Access Program (MAP) to provide access to CTL019  for acute lymphoblastic leukemia (ALL) or diffuse large b-cell lymphoma (DLBCL) patients with out of specification leukapheresis product and/or manufactured tisagenlecleucel out of specification for commercial release
99 years and younger
All genders
The purpose of this Treatment Plan is to allow access to tisagenlecleucel (CTL019) for eligible patients diagnosed with acute lymphoblastic leukemia (ALL) or large b-cell lymphomas who are unable to receive commercially manufactured product due to failure of the incoming apheresis material or outgoing product to meet the commercial specifications …
 A Study of Venetoclax (ABT-199) in Combination with Liposomal Vincristine in Patients with Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia
18-99 years
All genders
Phase 1
Interventional
This study is being done to determine what effects the therapy venetoclax has on acute lymphoblastic leukemia (ALL).This investigational therapy will be added to what is a standard, liposomal vincristine, to treat relapsed ALL.
99 years and younger
All genders
Evaluate the feasibility of MATCHBox receiving and organizing all data needed for assignment to a myeloMATCH clinical trial or Tier Advancement Pathway (TAP) within 72 hours of MDNet receipt of all required specimens for initial therapy and within 10 days for subsequent therapy.
99 years and younger
All genders
The RECHARGE program includes two separate trials, RECHARGE: Women and RECHARGE: Minorities. The objectives of the RECHARGE program are to: 1. Compare the treatment effect of PCI vs CABG on survival and QOL improvement in women (RECHARGE:Women) 2. Compare the treatment effect of PCI vs CABG on survival and QOL …
99 years and younger
All genders
This is an OLE for all subjects we currently have enrolled in BI 1305-0014 and 1305-0023. Subjects will be on either 9 mg or 18 mg of IP based on results from the current studies. Procedures involve safety labs, lung function testing, clinical labs, ECGs, PEs, AE collection.
 RECOVER: Safety and Effectiveness of VNS Therapy  System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
18-99 years
All genders
The research study is being conducted to determine if active VNS (Vagus Nerve Stimulation) Therapy helps depression subjects compared to a no-stimulation control group. Patients with an established diagnosis with Treatment-Resistant Depression (TRD) and have been referred for treatment with the VNS Therapy® System will potentially qualify to participate in …
99 years and younger
All genders
Reliance Agreement requested with VUMC (IREx). Creation of an observational phenotyping cohort of patients with acute respiratory distress syndrome, pneumonia or sepsis. Clinical risk factors, molecular phenotypes, and illness trajectories during the acute and recovery phases of these critical illness syndromes to be assessed. Full study protocol (Protocol A) describes …
99 years and younger
All genders
There are two components of this international, multicenter study: Registry A standardized genetic screening and a prospective, standardized, cross-sectional clinical data collection. Enrollment is open to all genes on the RD Rare Gene List Natural History Study A prospective, standardized, longitudinal Natural History Study Enrollment opens gene-by-gene, based on funding …
99 years and younger
All genders
Phase 2 open-label, single-arm clinical trial evaluating the efficacy and safety of neoadjuvant olaparib + LHRH agonist administered for 6 months prior to radical prostatectomy (RP) in men with unfavorable intermediate-risk or high-risk localized prostate cancer. All patients must have confirmed germline or somatic BRCA1/2 gene mutation. We would like …
99 years and younger
All genders
This is an expanded access protocol that will be conducted at sites qualified and approved to treat subjects with lisocabtagene maraleucel. Sometimes when lisocabtagene maraleucel is manufactured the drug does not pass all the testing results to be called lisocabtagene maraleucel. The expanded access protocol will be used to allow …