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Found 136 Lymphocytic Leukemia, Acute trials

A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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UPCC 20319 GBM AGILE: Global Adaptive Trial Master Protocol: An International, Seamless Phase II/III Response Adaptive Randomization Platform Trial Designed To Evaluate Multiple Regimens In Newly Diagnosed and Recurrent GBM
18 years or above
All genders
Phase 2/3
Interventional
This study investigates therapies for glioblastoma, a type of brain cancer. The purpose of this study is to evaluate multiple therapies for newly diagnosed and recurrent glioblastoma using a response adaptive randomization platform. This method assigns participants to different study arms based on their performance, aiming to identify effective treatments …
99 years or below
All genders
All objectives are listed in section 3 of the protocol, but the primary objective is to evaluate the long-term safety of RAP-219 in participants with focal onset seizures. The primary endpoint is the incidence of treatment-emergent adverse events (TEAEs). The secondary objectives and their associated endpoints can be found in …
18 years or above
All genders
Interventional
This study investigates whether additional regional nerve blocks can reduce pain and anxiety in adults undergoing Mohs micrographic surgery for skin cancers on the face and scalp. Participants will be randomly assigned to one of two study arms: one receiving a placebo nerve block with sterile saline and the other …
99 years or below
All genders
This study investigates the use of investigational treatment for patients who receive a nonconforming version of a specific investigational medication. The purpose is to evaluate whether the potential benefits of using this nonconforming treatment outweigh the potential risks for patients.Participants in this study will receive a nonconforming version of the …
18 years or above
All genders
Phase 1
Interventional
This study investigates the use of CART123 cells in combination with ruxolitinib for patients with relapsed or refractory acute myeloid leukemia (AML). The purpose of this study is to assess the safety and early effectiveness of this combination treatment. Participants will receive a single infusion of CART123 cells after being …
99 years or below
All genders
The primary objective of the IMPROVE-AD trial is to determine whether an upfront invasive strategy of TEVAR plus medical therapy reduces the occurrence of a composite endpoint of all-cause death or major aortic complications compared to an upfront conservative strategy of medical therapy with surveillance for deterioration in patients with …
100 years or below
All genders
Phase 3
Interventional
This study investigates the long-term safety and efficacy of patients who have undergone CAR-T cell therapy. The purpose of this study is to monitor these patients for 15 years following their last CAR-T infusion to assess any delayed adverse events, check for replication competent lentivirus, and evaluate long-term efficacy, including …
18 years or above
Female
Phase 1
Interventional
This study investigates the safety and tolerability of an investigational medication for women with hormone receptor-positive (HR+) and human epidermal growth factor receptor 2 negative (HER2-) metastatic breast cancer. The study focuses on participants whose tumors have mutations in the PIK3CA gene. The purpose is to find the safest and …
18 years or above
All genders
Phase 2/3
Interventional
This study investigates treatments for non-small cell lung cancer (NSCLC) by using a method called genomic screening. The purpose of this study is to determine which type of cancer trait, known as a biomarker, a participant has. This information helps assign participants to different sub-studies within a larger protocol called …
18 years or above
All genders
The purpose of this study is to investigate the use of nonconforming lisocabtagene maraleucel in patients who were prescribed lisocabtagene maraleucel as part of their routine care. Lisocabtagene maraleucel is a type of treatment that involves using modified cells to fight certain diseases. Sometimes, the manufactured product does not meet …