A listing of Lymphocytic Leukemia, Acute medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of this research study will be to evaluate the safety and effectiveness of two investigational drugs, All-trans retinoic acid (ATRA) and Retifanlimab (anti-PD1 monoclonal antibody), in treating recurrent IDH-mutant gliomas. Objective radiographic response (CR + PR + MR) using Response Assessment in Neuro-Oncology (RANO) criteria by measurable disease …
This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System plus anticoagulation compared to anticoagulation alone for intermediate-risk acute PE. Up to 1200 subjects with intermediate-risk acute PE will be randomized. All subjects who sign informed consent and who meet all of the inclusion criteria and none …
This will be a prospective, observational, multicenter study. All implants will be placed in the maxilla or mandible for already established participants at Penn Dental Medicine. The patient will either have a temporary prosthesis placed (out of occlusion) immediately (during the same implant placement visit or within 48 hours) or …
A multicentre, non-interventional, post-market registry to collect safety and performance data on all commercially available knitted and woven grafts, and cardiovascular patches. Data will be collected both retrospectively and prospectively.
The purpose of this research study is to better understand anxiety fluctuations during the perinatal period using technology-based daily assessment of mood, anxiety, sleep, and activity levels. This study uses a daily mood diary to monitor anxiety and wearable technology to track sleep and physical activity. All tasks during the 28-day …
The primary objective of the IMPROVE-AD trial is to determine whether an upfront invasive strategy of TEVAR plus medical therapy reduces the occurrence of a composite endpoint of all-cause death or major aortic complications compared to an upfront conservative strategy of medical therapy with surveillance for deterioration in patients with …
Specific Aims include: Coordinate all human PET and MR imaging at U Penn, UCSF, Yale and WU. Standardize inclusion/exclusion criteria for patient groups - idiopathic PD, MSA, PSP, FTD and healthy controls. Harmonize PET scanning protocols and devices. Generate and coordinate all regulatory protocols including local Radiation Safety or Radioactive …
This study is designed to investigate the safety, diagnostic performance, and clinical usefulness of Gleolan for the real time detection and visualization of meningiomas during tumor resection surgery. Potential patients who sign informed consent will be screened for eligibility before receiving an oral solution of Gleolan 3 hours prior to …
To evaluate the efficacy of NTLA-2001, as measured by the composite risk of CV-related mortality and CV events (urgent HF visits and hospitalizations due to HF, MI, arrhythmia, or stroke), compared to placebo Composite endpoint comprising Cardiovascular related mortality and frequency and timing of Cardiovascular events (urgent Heart Failure visits …
PRIMARY OBJECTIVE: To demonstrate that treatment of Invasive Candidiasis/ Candidemia with IV echinocandin followed by oral ibrexafungerp is non-inferior to IV echinocandin followed by oral fluconazole based on 30-day all-cause mortality (ACM). SECONDARY OBJECTIVES: To demonstrate that treatment of Invasive Candidiasis/ Candidemia with intravenous (IV) echinocandin followed by oral ibrexafungerp …