Found 139 Neoplasms trials
A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study will evaluate safety, clinical activity, and PK of ZN-c3 in subjects with platinum-resistant, high grade, serous ovarian, fallopian tube, or primary peritoneal cancer. Part 1a locally advanced/metastatic solid tumors with mutations in MRN complex genes or CCNE1 gene amplification. Part 1b primary peritoneal cancer. Part 2: PROC allocated …
This study is open to adults with advanced cancer in the biliary tract, pancreas, lung, or bladder for whom previous treatment was not successful or no treatment exists, to find out whether a medicine called BI 907828 helps. BI 907828 is a so-called MDM2 inhibitor that is being developed to …
Please refer to Protocol Section 2 (Objectives and Endpoints) Please refer to Protocol Section 2 (Objectives and Endpoints) Please refer to Protocol Section 2 (Objectives and Endpoints)
This study has a mono therapy arm and a combination therapy arm. The main purpose of the mono therapy arm is to test the safety and tolerability of ART4215 in humans. The main purpose of the combination therapy arm is to test ART4215 compared to and in combination with talazoparib.
The purpose of this study is to compare the usual treatment alone to using one year of olaparib. We will enroll subject who have been diagnosed with pancreatic cancer and have undergone surgery to remove the cancer. Only patients who are found to have a BRCA1, BRCA2 or PALB2 mutation …
This phase II/III trial compares the effect of adding chemotherapy before and after surgery versus after surgery alone (usual treatment) in treating patients with stage II-III gallbladder cancer. This study will determine whether giving chemotherapy before surgery increases the length of time before the cancer may return and whether it …
The purpose of this study includes the following: · To test the efficacy and safety of the Study Drug and to find out what effects, good and/or bad, it has on you and your cancer. · To understand how the body absorbs and processes the Study Drug by measuring the …
This research study is being done to study the safety and toxicity of proton whole pelvis radiation, a type of external beam radiation treatment, for gynecologic cancers after surgery. Currently, for such gynecology cancers, Image- guided Intensity Modulated Radiation Therapy (IG-IMRT) is being done after hysterectomy as the standard treatment. …
To evaluate safety of ultrahypofractionated proton therapy to the prostate and whole pelvis with HDR brachytherapy boost. The technique will be deemed safe if 10% of patients experience a CTCAE grade 3 or higher genitourinary or gastrointestinal toxicity cumulatively over the first year of treatment.To evaluate for multiple domains of …
