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Found 57 Breast Cancer trials
A listing of Breast Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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This study investigates the effectiveness and safety of an investigational medication, a bi-specific antibody-drug conjugate, for patients with advanced triple-negative breast cancer (TNBC) or ER-low, HER2-negative breast cancer (BC). These patients have not received prior treatment for their condition and are not eligible for certain standard therapies. The investigational medication …
This study investigates personalized medicine approaches to determine which investigational medications are most effective for different types of breast cancer tumors. The purpose is to identify early indicators of treatment response, such as tumor analysis before surgery using MRI images, tissue, and blood samples, to predict treatment success.Participants will undergo …
This study investigates the safety and effects of an investigational radioligand therapy in adults with advanced or metastatic solid tumors that have high levels of fibroblast activation protein (FAP). The study aims to understand how the investigational therapy interacts with FAP. The purpose of this study is to evaluate the …
This study investigates the effectiveness of different treatment combinations for Stage I HER2-positive breast cancer. The purpose of this study is to compare the side effects and long-term benefits of two different HER2-directed therapies used after surgery. Participants will be randomly assigned to one of two study arms: one receiving …
This study investigates the safety and effectiveness of an investigational imaging agent in female patients who are undergoing surgery for ductal carcinoma in situ (DCIS) or early-stage breast cancer. The purpose of this study is to understand how the imaging agent works in the body and its potential to aid …
This study investigates an investigational medication for patients with HER2-positive metastatic breast cancer. The purpose of this study is to evaluate the effects of this investigational medication in patients who have previously been treated with a specific therapy called T-DXd.Participants in this study will receive the investigational medication through an …
This study investigates the effectiveness of a quantitative HER2 assay in distinguishing between patients with HER2 IHC1+ metastatic breast cancer who respond to treatment and those who do not. The purpose is to determine if this assay can reliably identify patients who are likely to benefit from receiving investigational medications …
This study investigates the use of two investigational medications to treat residual triple negative breast cancer. The purpose of this study is to see if the combination of sacituzumab govitecan and atezolizumab can be effective for patients who have residual cancer in the breast or lymph nodes and have circulating …
This study investigates the effectiveness of different endocrine therapies for treating male breast cancer. This research aims to determine how well male breast cancer responds to preoperative endocrine therapy and which regimen is most effective. Participants will receive treatment with one of four endocrine therapy combinations, including standard treatments like …
Obtain patient information (name, age, gender, genetic testing information, OncoType Dx recurrence scores, breast cancer diagnosis information (hormone receptor status, TNM, histology), age at diagnosis) collected from the electronic medical record of approximately 70 patients to perform age-matched control analyses.
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