Found 24 Heart Failure trials
A listing of Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of DT PAS PSR is to -Provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products for their intended use -To further confirm safety and effectiveness of the HVAD System when used as intended for DT, in real-world clinical practice The purpose of Apogee …
The OPTIMIZER Smart Post-Approval Study (PAS) is a single arm open label study of 620 participants receiving an OPTIMIZER implant as standard of care. Patients to be included will have NYHA functional class III symptoms and a left ventricular ejection fraction of 25-45%.
This open-label study is designed to evaluate the long-term safety and tolerability of acoramidis in participants with ATTR-CM, administered on a background of stable heart failure therapy. This study follows the randomized, double-blind, placebo-controlled Study AG10-301 which was designed to examine safety and efficacy in this same population.
In patients with heart failure, there is disassociation between exercise capacity and cardiac performance. My research focuses on understanding the peripheral (i.e. non-cardiac) mechanisms of exertional intolerance in heart failure patients. We have developed non-invasive techniques to assess skeletal muscle oxidative capacity, the diffusional conductance for oxygen across the skeletal …
The purpose of the study is to test the use of a drug called bromocriptine for women who have a condition called Peripartum cardiomyopathy or PPCM. PPCM means you have a weak heart after giving birth. The study will look at how the heart muscle improves in women taking bromocriptine …
The INTEGRA D study will evaluate the safety and efficacy of the CCM D System in patients with heart failure symptoms despite being on GDMT and have an LVEF 40%.The This is designed as a single arm, prospective, multicenter study of 300 subjects that will establish that the device can …
This is a prospective, multicenter observational study to identify clinical, genetic and imaging predictors of clinical outcome in patients with suspected non-compaction cardiomyopathy Many healthy people have increased trabeculations without consequences, however, some may develop blood clots, heart rhythm disorders or heart failure later in life. Currently we cannot predict who …
The purpose of the study is to compare how amlodipine versus metoprolol effect blood pressure in people with HFpEF. While hypertension is the most common risk factor for HFpEF, there is little evidence on the potential role of common antihypertensive medications, specifically calcium channel blockers (like amlodipine) and β-blockers …
The OPTIMIZER® INTEGRA CCM-D System, also known as a “Cardiac Contractility Modulation – Defibrillator” is an investigational device system that combines CCM® therapy and ICD therapy into one device. CCM therapy has been shown to improve heart failure symptoms. This clinical trial is designed to determine if the OPTIMIZER® INTEGRA …
The research study is being conducted to collect blood specimens to evaluate a new diagnostic blood test that will help physicians diagnose individuals that may have new symptoms of heart failure or to determine the severity in those with heart failure. Samples will be used to evaluate the usefulness and …
