A listing of Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The broad objective of this proposed research protocol is to have heart tissue specimens available to use for studies designed to help us better understand the causes and manifestations of human heart failure. The broad objective of this proposed research protocol is to have heart tissue specimens available to use …
The aim is to prospectively evaluate the efficacy and mechanism of benefit of HI-CRT vs. BIV CRT in patients with Right Bundle Brank Block (RBBB). Left Ventricular Ejection Fraction (LVEF) will be assess at 6 months following HIS CRT Vs. BIV CRT implant in Heart Failure patients with RBBB.
The purpose of this study is to evaluate the effect of breath training on patients with systolic heart failure. The study evaluates patients and incorporates the use of smart phone technology for breath training at baseline and at three and six months, using the 6-minute walk test, a standard heart …
Prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the CARILLON Mitral Contour System in treating functional mitral regurgitation associated with heart failure.
This research study seeks to validate how echocardiogram (echo) data predicts response to cardiac resynchronization therapy (CRT) provided by a CRT device with a defibrillator (CRT-D) in individuals without the heart arrhythmia abnormality left bundle branch block (LBBB). It also aims to identify new variables recorded from electrocardiograms (ECG) or …
This study will determine if ziltivekimab, a monoclonal antibody, can be used to treat people living with heart failure and inflammation. Previous studies showed that ziltivekimab can lower inflammation, which may have a positive effect on heart failure symptoms. The HERMES study will look more into this effect. Also, the …
This study aims to test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality of life, physical activity, heart failure hospitalization, mortality) and comparative safety in relation to device-related complications. This is for patients with heart failure who are already receiving current …
To evaluate the efficacy of NTLA-2001, as measured by the composite risk of CV-related mortality and CV events (urgent HF visits and hospitalizations due to HF, MI, arrhythmia, or stroke), compared to placebo Composite endpoint comprising Cardiovascular related mortality and frequency and timing of Cardiovascular events (urgent Heart Failure visits …
This is a prospective pilot study in which all eligible subjects will be randomized to treatment in the first phase and those with persistent or recurrent heart failure after Phase 1 therapy, may subsequently qualify to be randomized into Phase 2.