Found 33 Depression trials
A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The research study is being conducted to determine if active VNS (Vagus Nerve Stimulation) Therapy helps depression subjects compared to a no-stimulation control group. This trial has is currently only recruiting bipolar subjects. Patients with an established diagnosis with Treatment-Resistant Depression (TRD), Bipolar I or II, and have been referred …
To determine the efficacy of VLS-01-BU compared with placebo in improving depressive symptoms in participants with TRD 4 weeks after initiating treatment
Primary Objective: To compare the efficacy of 2 doses of BHV-7000 to placebo as an adjunctive therapy for refractory focal onset epilepsy as measured by the change from baseline in 28-day average seizure frequency. Secondary Objcetives: -To compare the efficacy of 2 doses of BHV-7000 to placebo as adjunctive therapy …
Living with HIV and struggling with depression or both depression and memory problems?We are looking for participants for a research study comparing two medications: pramipexole extended release (ER) and escitalopram.
The research study is being conducted to examine the effects of accelerated intermittent theta-burst stimulation (aiTBS), a form of transcranial magnetic stimulation, to the inferior parietal lobe (IPL) in a sample of BD patients who are currently depressed. This project will recruit patients aged 22-65 with symptoms of bipolar depression …
Millions of women worldwide have accidental leakage of urine they cannot control after giving birth. Dealing with this problem can be embarrassing and can even add to feelings of anxiety or depression. If you recently delivered your first baby and are experiencing this sort of bothersome accidental bladder leakage, the …
The primary objective is to compare the Minder System with standard of care as a means of assisting in obtaining any of the following actionable events: diagnosis, seizure characterization, surgery evaluation, event classification, paroxysmal events, psychogenic nonepileptic seizures, or treatment effects. The secondary objectives include comparing the time to the …
The research study is being conducted to study brain patterns of negative emotion and develop personalized brain stimulation protocols to disrupt these patterns with transcranial magnetic stimulation (TMS). First, we will use functional Magnetic Resonance Imaging (fMRI) data to generate a negative affect map for each subject. Then, we will …
To test if TMS to MRI-guided cortical targets can create neuronal activity changes in downstream regions of interest To determine if TMS-sEEG is a valid research approach to study circuit engagement and specific connections of deep brain nuclei in the human brain To investigate the effects of clinically relevant TMS …
Objectives 1) Evaluate the safety and feasibility of focused ultrasound to three brain targets Changes in VAS scores, Changes in pre- and post-study imaging, Changes in symptomatic checklist survey data Psychophysiology (heart rate, respiration, skin conductance), Y-BOCS score
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