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Found 16 Depression trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 - 65
All genders
Interventional
The research study is being conducted to test the efficacy of a new psychotherapeutic strategy, closed loop real time fMRI neurofeedback, in reducing negative attention bias and depressive symptoms. Participants are being asked to voluntarily participate in a research study because they are between the ages 18-65 and currently experiencing …
 Disentangling the Role of Depression in Hypersomnia
21 - 55
All genders
The goal of this study is to further our understanding of the relationship between depression and hypersomnia by examining mood-relevant domains of slow wave sleep and reward function.
 RECOVER: Safety and Effectiveness of VNS Therapy  System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
18 - 99
All genders
The research study is being conducted to determine if active VNS (Vagus Nerve Stimulation) Therapy helps depression subjects compared to a no-stimulation control group. Patients with an established diagnosis with Treatment-Resistant Depression (TRD) and have been referred for treatment with the VNS Therapy® System will potentially qualify to participate in …
99 or below
All genders
The purpose of this research study is to evaluate whether adding stimulation of the subcallosal cingulate white matter using the investigational Infinity Deep Brain Stimulation (DBS) system in treatment of Major Depressive Disorder is safe and beneficial. This study is looking for 6 patients with Major depressive disorder to participate. …
99 or below
All genders
Primary Objective: To compare the efficacy of 2 doses of BHV-7000 to placebo as an adjunctive therapy for refractory focal onset epilepsy as measured by the change from baseline in 28-day average seizure frequency. Secondary Objcetives: -To compare the efficacy of 2 doses of BHV-7000 to placebo as adjunctive therapy …
 Integrating Brain, Neurocognitive, and Computational Tools in Opioid Use Disorder (OUD) to Characterize Executive Function and to Predict Clinical Outcomes
18 - 60
Accepts healthy volunteer
All genders
Phase 3
The 5-year K01 Mentored Research Scientist proposal will employ brain, neurocognitive, and computational tools (e.g., machine learning) to understand the impact of opioid-use disorder (OUD) and common co-occurring issues on executive function and clinical outcomes.
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