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Found 40 dm-cardiovascular-medicine trials

A listing of dm-cardiovascular-medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Matching Perfusion and Metabolic Activity in HFpEF
18 years - 99 years
All genders
Phase 2
The goal of the MPMA Study is to test whether Potassium Nitrate, with and without Propionyl-L-Carnitine and Nicotinamide Riboside, improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity in participants with Heart Failure with Preserved Ejection Fraction. We are assessing whether these supplements, either together or separate, help relieve …
99 years or below
All genders
The purpose of the study is to test the use of a drug called bromocriptine for women who have a condition called Peripartum cardiomyopathy or PPCM. PPCM means you have a weak heart after giving birth. The study will look at how the heart muscle improves in women taking bromocriptine …
18 years or above
All genders
Interventional
This study investigates peripheral artery disease (PAD).The study evaluates how the investigational medication affects inflammation in the arteries.Who can participate: Adults aged 18 and older with peripheral artery disease who are willing to follow study procedures can participate. Those using certain anti-inflammatory medications or with specific medical conditions are excluded.Study …
99 years or below
All genders
This is a 2-part, open-label study in approximately 9 adults with oHCM. Part A of the study consists of 3 cohorts of approximately 3 participants each administered a single dose of EDG-7500. Part B of the study is an optional multiple-dose treatment period in which approximately 9 participants will receive …
18 years or above
All genders
Interventional
This study investigates the effects of an investigational medication on nonobstructive hypertrophic cardiomyopathy (noHCM).The study evaluates the safety and potential benefits of the investigational medication in improving exercise capacity and cardiac function.Who can participate: Adults with a diagnosis of hypertrophic cardiomyopathy who can take oral medication and comply with study …
18 years or above
All genders
Interventional
This study investigates the safety and effectiveness of an investigational atrioventricular interval modulation (AVIM) algorithm in patients with dual-chamber pacemakers.The study evaluates how well the investigational AVIM algorithm works when downloaded into a specific type of pacemaker. It looks at whether this algorithm can be safely used and how effective …
18 years or above
All genders
Interventional
This study investigates heart failure due to left ventricular systolic dysfunction. It focuses on comparing two types of pacing: His bundle branch pacing and Left bundle branch pacing.The study evaluates the effectiveness and safety of these pacing methods. It looks at how they impact quality of life, physical activity, and …
99 years or below
All genders
Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol
The SAK HFpEF Trial
18 years - 99 years
All genders
Phase 2
The goal of the SAK study is to test whether Empagliflozin, with and without Potassium Nitrate, improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity in participants with Heart Failure with Preserved Ejection Fraction. We are assessing whether this medication and supplement, either together or separate, helps relieve symptoms …
18 years or above
All genders
Phase 3
Interventional
This study investigates symptomatic hypertrophic cardiomyopathy. The condition is being studied to understand changes in symptoms and functional limitations when treated with an investigational medication compared to a placebo.The purpose of this study is to evaluate how safe and effective the investigational medication is for people with the condition. It …
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