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Found 40 dm-cardiovascular-medicine trials
A listing of dm-cardiovascular-medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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PURPOSE We aim to conduct a prospective observational study to test the central hypothesis that myocardial LM begins early after STEMI, as a response to myocardial hemorrhage and reperfusion injury, and determines future susceptibility to malignant arrhythmia. Study participants will be 175 (allowing for 25 dropouts) men and women 2 …
This study investigates the use of an investigational catheter and ablation system for individuals with scar-related monomorphic ventricular tachycardia.The purpose of this study is to evaluate the feasibility of using the Sphere-9 Catheter and Affera Ablation System for treating this condition. The study will focus on assessing the safety and …
This study investigates heart failure with severely reduced ejection fraction. It will explore how the investigational medication may affect this condition.The study evaluates the effectiveness and safety of the investigational medication in reducing risks associated with heart failure, such as cardiovascular events and other serious outcomes.Who can participate: Adults aged …
This study investigates the effectiveness and safety of the Cordella PA Sensor System in patients with NYHA Class III Heart Failure. The purpose of this study is to compare the outcomes of using this system against a set performance goal.This study evaluates how well the Cordella PA Sensor System works …
This study investigates calcific aortic valve stenosis. The purpose of this study is to evaluate if the investigational medication slows the progression of this condition in adults.The study will focus on evaluating the safety, tolerability, and how the investigational medication is processed in the body. It will also look at …
This study investigates genetic and familial dilated cardiomyopathy (DCM).The study evaluates the safety and effectiveness of an investigational medication compared to a placebo.Who can participate: Adults diagnosed with genetic or familial DCM, with stable symptoms and certain heart function criteria, may participate. Participants should not have DCM due to other …
Currently, there are no approved evidence-based medicines for the treatment of symptoms in patients with nHCM. In the absence of proven therapies for the treatment of symptomatic patients with nHCM, this study employs a randomized, placebo-controlled, parallel-group design evaluating ninerafaxstat added to the standard of care (SoC) to maintain clinical …
This study is being performed to evaluate the Thermedical SERF Ablation System to reach intractable, deep circuits supporting recurrent VT. Due to the limitations of VT success rates, such as unable to ablate clinical VT circuits in 10% or more of subjects and the recurrence for VT in 50% or …
The objectives of the Randomized Arm are 1) Demonstrate improvement in survival when non-inotrope dependent advanced HF patients are treated with the HM3 left ventricular assist system (LVAS) compared to being managed on medical therapy alone; and 2) To establish an objective disease-state criteria to trigger referral for a HM3 …
The study has two treatment arms: conventional voltage mapping and ablation (control arm) and isochronal late activation mapping (ILAM) and ablation (investigational arm). This is a multicenter, prospective, parallel, randomized controlled trial to test for non-inferiority with an ILAM-guided VT ablation compared to conventional voltage- based ablation.
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