Found 32 dm-cardiovascular-medicine trials
A listing of dm-cardiovascular-medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Phase 2
This study will test whether Potassium Nitrate (KNO3), with and without Propionyl-L-Carnitine (PLC) and Nicotinamide Riboside (NR), improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity (SkM OxPhos) in participants with Heart Failure with Preserved Ejection Fraction (HFpEF). This study will also test whether the response to supplemental oxygen …
Phase 2
The research team aims to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial. We will randomize patients post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine. Patients will be on study drug or placebo for 1 month but will …
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
Compare the safety and efficacy of the Bare Temporary Spur Stent System in subjects with infrapopliteal critical limb ischemia (CLI) to a pre-defined performance goal based on standard percutaneous transluminal balloon angioplasty (PTA). Population: infrapopliteal CLI, Rutherford class 4-5, not considered amenable to conservative medical therapy and require endovascular intervention …
Primary: To determine whether TcMS can reduce the burden of VT in patients with VT storm. Secondary: 1. To determine whether low frequency TcMS or TcMS with TBS is more effective at reducing the burden of VT in patients with VT Storm. 2. To determine the safety of TcMS in …
Please see Section 3 of the full protocol. Please see Section 3 of the full protocol. Please see Section 3 of the full protocol.
Investigational Atrioventricular Interval Modulation (AVIM) software will be loaded onto commercially available Pacemakers (PPM), such as the Medtronic Azure/Astra devices. Therefore, the Azure/Astra devices will be considered investigational while the AVIM is present. AVIM therapy is indicated for the reduction of blood pressure in patients with dual PPM and uncontrolled …
This trial evaluates the effects of His or left bundle branch pacing (LBBP) comparative to biventricular pacing on quality of life, exercise capacity, hospitalization for heart failure, and mortality in patients with HF and conduction system disease. Study population is patients with heart failure with reduced ejection fraction (HFrEF) less …
1.Compare the impact on submaximal exercise endurance of Empa, with and without KNO3, as compared to active control (Potassium Chloride, KCl).2.Assess the impact of Empa, with and without KNO3, on SkM OxPhos using novel in vivo MRI-based imaging techniques that quantify SkM OxPhos and intramuscular perfusion with exercise3.Assess the impact …
To determine the changes in symptoms and functional limitations in patients with symptomatic hypertrophic cardiomyopathy (HCM) treated with sotagliflozin as compared to placebo.
