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Found 40 dm-cardiovascular-medicine trials

A listing of dm-cardiovascular-medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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99 years or below
All genders
The purpose of this study is to characterize the safety and effectiveness of the Sphere-9 Catheter and Affera Ablation System, when used in conjunction with the Affera Mapping System or Affera Integrated Mapping System, in patients undergoing redo ablation for symptomatic recurrent paroxysmal or persistent atrial fibrillation after a single …
99 years or below
All genders
The objective of this study is to assess the safety and efficacy of the Supira System in providing temporary cardiovascular hemodynamic support in patients undergoing HRPCI. Eligible patients approved by the Patient Screening Committee (PSC) will be randomized to undergo HRPCI with either the Supira System (investigational device) or the …
99 years or below
All genders
This study will evaluate whether the Impella 5.5 heart pump can safely support patients with severe heart failure and cardiogenic shock while doctors optimize their recommended heart failure medications. Patients at multiple hospitals will receive the device, and researchers will assess its safety and feasibility in real-world clinical use. The …
INFINITY-Prospective Cohort Study of Mechanistic Associations between Intra-Myocardial Fat Deposition and Ventricular Tachycardia in Ischemic Cardiomyopathy
18 years - 99 years
All genders
This study will focus on fat buildup inside the heart muscle, a newly recognized factor that makes patients vulnerable to such fast heart rates, or ventricular tachycardia, after a heart attack. This work may identify more successful strategies for curing dangerously fast heart rates. Adult subjects with prior history of …
PRESTA- Promoting Recovery after Stroke with Amantadine
18 years - 99 years
All genders
Phase 2
The research team aims to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial. We will randomize patients post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine. Patients will be on study drug or placebo for 1 month but will …
Brain Arterio-Venous Metabolomic Profiling
18 years - 99 years
All genders
The research study is being conducted to better understand brain metabolism, i.e. how the brain uses and consumes the various nutrients that are available in the blood. Changes in brain metabolism have been implicated in dementia and psychiatric disorders, as well as short- and long-term outcomes of traumatic brain injury …
A  study of near infrared imaging of myocardial scar and epicardial ganglionated plexus in patients undergoing cardiac surgery
18 years - 99 years
All genders
Observational
To determine the feasibility of near infrared (NIR) imaging of myocardial scar and epicardial adipose tissue in patients undergoing cardiac surgery.
99 years or below
All genders
This study aims to identify genotypic and phenotypic characteristics that are associated with the clinical heterogeneity and outcomes of hypertrophic cardiomyopathy (HCM), using the Sarcomeric Human Cardiomyopathy Registry (SHaRe).
99 years or below
All genders
The primary objective of this trial is to test whether FFRangio®-guided treatment is noninferior to conventional pressure wire-guided treatment in patients with coronary artery disease being evaluated for percutaneous coronary intervention (PCI) with respect to major adverse cardiac events (MACE) at one year
UPCC 28922 AbatacepT foR ImmUne checkpoint inhibitor associated Myocarditis (ATRIUM): A Phase 3, Investigator-Initiated, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Abatacept Compared to Placebo in Participants with Immune Checkpoint Inhibitor Associated Myocarditis
18 years or above
All genders
Phase 3
Interventional
This study investigates the effects of an investigational medication compared to a placebo in participants with myocarditis linked to immune checkpoint inhibitors (ICI). This condition can occur as a side effect of cancer treatments that use ICIs to enhance the body's immune response against cancer cells. The purpose of this …
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